(3R,4S)-3-amino-4-(3-fluoro-5-methoxypyridin-2-yl)pyrrolidin-2-one CAS 1784748-24-8
| CAS No. | 1784748-24-8 |
| Molecular Formula | C10H12FN3O2 |
| Molecular Weight | 225.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3R,4S)-3-amino-4-(3-fluoro-5-methoxypyridin-2-yl)pyrrolidin-2-one (CAS 1784748-24-8), molecular formula C10H12FN3O2 and molecular weight 225.22 g/mol, is a CATO reference standard with documented purity and traceability.
(3R,4S)-3-amino-4-(3-fluoro-5-methoxypyridin-2-yl)pyrrolidin-2-one (C10H12FN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3R,4S)-3-amino-4-(3-fluoro-5-methoxypyridin-2-yl)pyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12FN3O2 |
| Molecular Weight | 225.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 2-Acetamido-3-(3-fluorophenyl)propanoic acid (CAS 17607-28-2)
- 3-Fluoro-4-nitro-2-(piperidin-1-yl)pyridine (CAS 1881330-20-6)
- 2-Acetamido-3-(4-fluorophenyl)propanoic acid (CAS 17481-06-0)
- 4-Fluoro-3,3-dimethyl-7-nitro-2,3-dihydro-1H-inden-1-ol (CAS 1951441-47-6)
- 1,4-dioxepan-6-ol (CAS 28544-95-8)
- tert-Butyl (R)-2-(hydroxymethyl)aziridine-1-carboxylate (CAS 1286768-91-9)
- (S)-tert-Butyl 2-isobutylpiperazine-1-carboxylate hydrochloride (CAS 1217456-63-7)
- 4-(3-Fluorophenyl)but-3-enoic acid (CAS 127404-67-5)
- 5-(Sec-butyl)isoxazol-3-amine (CAS 1469007-95-1)
- cis-1,4-dimethoxycyclohexane (CAS 28046-68-6)
- 5-(Benzylthio)-1-methyl-1H-pyrazol-4-amine hydrochloride (CAS 2345666-85-3)
- 2-(4-Amino-2-methoxyphenoxy)-1-morpholinoethanone (CAS 893764-78-8)
- tert-Butyl ((1S,3R)-3-(aminomethyl)cyclopentyl)carbamate (CAS 774213-03-5)
- Des-Phe22-Tirzepatide (CAS CATO-CPTD788951)
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