5-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid CAS 1784884-56-5
| CAS No. | 1784884-56-5 |
| Molecular Formula | C6H4F3NO2 |
| Molecular Weight | 179.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid.
5-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid (CAS 1784884-56-5) is a high-purity analytical reference standard with the molecular formula C6H4F3NO2 and a molecular weight of 179.10 g/mol.
Structurally, 5-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid (C6H4F3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 179.10 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4F3NO2 |
| Molecular Weight | 179.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related trifluoromethyl Standards
- 2-Methyl-5-(trifluoromethyl)oxazole-4-carbaldehyde (CAS 1211522-28-9)
- 5-(Trifluoromethyl)pyridine-2,4-diol (CAS 1227574-81-3)
- 5-(Trifluoromethyl)pyrazole-3-carboxamide (CAS 1276541-94-6)
- 3-(Trifluoromethyl)-1H-pyrrole-2-carboxylic acid (CAS 1367870-78-7)
- 2-(trifluoromethyl)-1h-pyrrole-3-carboxylic acid (CAS 147642-16-8)
- N-(1-(Trifluoromethyl)-1H-pyrazol-4-yl)formamide (CAS 1706444-25-8)
- 1-(Trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 1706464-09-6)
- 2-(Trifluoromethyl)pyridine-3,5-diol (CAS 1803825-27-5)
Recommended Standards
- 1-Cyano-2-(trifluoromethyl)cyclopropane-1-carboxylic acid (CAS 1801869-68-0)
- 1-Bromo-3-ethylpentane (CAS 1647-24-1)
- 4-(Difluoromethyl)-2-fluoropyridine-3,5-diol (CAS 1805005-33-7)
- 6-Amino-2-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 1513-70-8)
- Chloro[(R)-(+)-2,2'-bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride (CAS 944451-26-7)
- 1-(2-(3-(tert-Butylamino)-2-hydroxypropoxy)-5-fluorophenyl)butan-1-one maleate (CAS 88606-96-6)
- 3-(2,6-Dichlorophenyl)-2-hydroxypropanoic acid (CAS 1508654-31-6)
- 2,2,2-Trifluoro-N-(3-oxo-1-indanyl)acetamide (CAS 117391-20-5)
- 4-(1-(2-Chlorophenyl)-1H-pyrazol-5-yl)-6-(phenylthio)benzene-1,3-diol (CAS 876952-24-8)
- 1-Methyl-5-phenyl-1H-pyrazole-3-carbonyl chloride (CAS 859850-98-9)
- 2-Bromo-3-(2-tetrahydropyranyloxy)pyridine, 97% (CAS 93560-60-2)
- 2-Bromo-4-(3-bromophenyl)thiazole (CAS 886367-82-4)
- 7-(Benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine (CAS 720692-44-4)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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