2-(3-Chloro-4-fluorophenyl)-2,2-difluoroethan-1-ol CAS 1785261-10-0
| CAS No. | 1785261-10-0 |
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(3-Chloro-4-fluorophenyl)-2,2-difluoroethan-1-ol (CAS 1785261-10-0), a certified reference material (molecular formula C8H6ClF3O, MW 210.58 g/mol) for analytical method development and quality control.
The molecular framework of 2-(3-Chloro-4-fluorophenyl)-2,2-difluoroethan-1-ol (C8H6ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(3-Chloro-4-fluorophenyl)-2,2-difluoroethan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (2-Chloro-6-(trifluoromethyl)pyridin-4-yl)methanamine (CAS 1060810-25-4)
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- 1-Chloro-3-(2,2,2-trifluoroethoxy)benzene (CAS 106854-78-8)
- (4-Chloro-6-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1196154-09-2)
- S 2-Chloro-1-(2,3,4-trifluoro-phenyl)-ethanol 1204756-51-3 A1-02931 (CAS 1204756-51-3)
- 6-Chloro-N-methyl-4-(trifluoromethyl)pyridin-2-amine (CAS 1208081-32-6)
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Recommended Standards
- 175277-74-4 A812021 [3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]methanamine hydrochloride [3-chloro-5-(trifluoromethyl)-2-pyridinyl]methanamine hydrochloride (CAS 175277-74-4)
- 4-(Chloromethyl)-5-(difluoromethyl)-3-fluoropyridin-2-amine (CAS 1804488-63-8)
- 4-Chloro-5,6-dimethyl-2-(trifluoromethyl)pyrimidine (CAS 175277-32-4)
- 5-(Chloromethyl)-3-(difluoromethyl)-4-fluoropyridin-2-amine (CAS 1804488-67-2)
- 1-((4H-1,2,4-Triazol-4-yl)methyl)-1H-1,2,4-triazole (CAS 785010-95-9)
- 1-(2-Chloroethyl)-1h-1,2,4-triazole hydrochloride (CAS 1417569-97-1)
- N-(3-((3-(dimethylamino)propyl)amino)propyl)nicotinamide (CAS 404013-89-4)
- N-cyclohexyl-2-(methylthio)thieno[3,2-d]pyrimidin-4-amine (CAS 339018-92-7)
- 2,3-Difluoro-4-iodophenylacetic acid (CAS 887586-60-9)
- 4-[4-(tert-Butyl)phenyl]piperidine hydrochloride (CAS 1185297-19-1)
- (E)-tert-Butyl 4-(4-phenylbut-3-en-1-yl)piperazine-1-carboxylate (CAS 1353990-96-1)
- p-Benzoquinone-d4 (CAS 2237-14-1)
- H-Cys(tBu)-OH (CAS 2481-10-9)
- Glucagon (1-29) (CAS 16941-32-5)
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