3,3-difluoropiperidine-4-carboxylic acid hydrochloride CAS 1785367-71-6
| CAS No. | 1785367-71-6 |
| Molecular Formula | C6H9F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 201.60 g/mol gives 3,3-difluoropiperidine-4-carboxylic acid hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3,3-difluoropiperidine-4-carboxylic acid hydrochloride (CAS 1785367-71-6), a certified reference material (molecular formula C6H9F2NO2HCl, MW 201.60 g/mol) for analytical method development and quality control.
Structurally, 3,3-difluoropiperidine-4-carboxylic acid hydrochloride (C6H9F2NO2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 201.60 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9F2NO2 HCl |
| Molecular Weight | 201.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related difluoropiperidine Standards
- 1-Benzyl-4,4-difluoropiperidine-2,6-dione (CAS 1001337-74-1)
- 4,4-Difluoropiperidine-1-sulfonamide (CAS 1015170-98-5)
- 1-Benzyl-3,3-difluoropiperidine-4,4-diol (CAS 1067914-81-1)
- 4,4-Difluoropiperidine-1-sulfonyl chloride (CAS 1224929-81-0)
- Benzyl 4,4-difluoropiperidine-1-carboxylate (CAS 1226495-16-4)
- 3,5-Difluoropiperidine (CAS 1228631-14-8)
- 4,4-Difluoropiperidine-1-carbonyl chloride (CAS 1240057-29-7)
- Methyl 5,5-difluoropiperidine-2-carboxylate (CAS 1255663-85-4)
Recommended Standards
- Methyl 7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate (CAS 473994-46-6)
- 5-((Cyclopropylmethyl)thio)-1,3,4-thiadiazole-2-thiol (CAS 175277-92-6)
- N-Boc-L-Homoserine Methyl Ester (CAS 120042-11-7)
- (R)-1-(5-Chloro-2-(difluoromethoxy)phenyl)ethan-1-amine (CAS 1344934-50-4)
- 1-Allyl-5-bromopyrimidine-2,4(1H,3H)-dione (CAS 195508-02-2)
- tributyl(2-phenylethynyl)stannane (CAS 3757-88-8)
- 2,7-Dimethyldecane (CAS 17301-24-5)
- 2-(2-((Tetrahydrofuran-2-yl)methoxy)ethoxy)ethane-1-sulfonyl chloride (CAS 1340304-71-3)
- 5-(4-Methylphenyl)-1,3,4-thiadiazol-2-amine (CAS 26907-54-0)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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