5-(difluoromethyl)furan-2-sulfonyl chloride CAS 1785579-27-2
| CAS No. | 1785579-27-2 |
| Molecular Formula | C5H3ClF2O3S |
| Molecular Weight | 216.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(difluoromethyl)furan-2-sulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(difluoromethyl)furan-2-sulfonyl chloride (CAS 1785579-27-2) is a high-purity analytical reference standard with the molecular formula C5H3ClF2O3S and a molecular weight of 216.59 g/mol.
5-(difluoromethyl)furan-2-sulfonyl chloride (C5H3ClF2O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(difluoromethyl)furan-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3ClF2O3S |
| Molecular Weight | 216.59 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related difluoromethyl Standards
- 1-(Difluoromethyl)-1H-pyrazole-4-sulfonyl chloride (CAS 1006320-00-8)
- 1-((1-(Difluoromethyl)-1h-pyrazol-5-yl)methyl)piperazine (CAS 1245823-85-1)
- 1-{[1-(difluoromethyl)-1H-imidazol-2-yl]methyl}piperazine (CAS 923233-19-6)
- 4-(Difluoromethyl)-2-propylpyrimidine-5-carboxylic acid (CAS 1344101-95-6)
- Ethyl 4-(difluoromethyl)-2-methylpyrimidine-5-carboxylate (CAS 1598230-41-1)
- 2-(Difluoromethyl)-5-methoxy-4-methylpyridine-3-carboxamide (CAS 1805440-90-7)
- 2-(Difluoromethyl)-3-methoxy-4-methylpyridine-5-carboxamide (CAS 1805551-91-0)
- 2-(Difluoromethyl)-4-methoxy-6-methylpyridine-3-carboxamide (CAS 1805551-99-8)
Recommended Standards
- Methyl 2-(4-chloro-3-fluorophenyl)-2-oxoacetate (CAS 1379361-62-2)
- 4-Chloro-2-fluoro-3-formyl-5-methylbenzoic acid (CAS 2624417-79-2)
- Methyl 2-(3-chloro-5-fluorophenyl)-2-oxoacetate (CAS 1379340-40-5)
- 6-Fluoro-4H-benzo[1,3]dioxine-8-carbonyl chloride (CAS 321309-29-9)
- 4-Chloro-N-(2-((4-methyl-1,2,3-thiadiazol-5-yl)thio)ethyl)benzenesulfonamide (CAS 478063-53-5)
- 6-chloro-[1,2,4]triazolo[1,5-a]pyrimidine-2-carbaldehyde (CAS 749929-27-9)
- 2-((2,2-dimethoxyethyl)(nitroso)amino)-N-phenethylacetamide (CAS CATO-C3D-26205)
- Dimethyl (1R,2R)-rel-cyclopentane-1,2-dicarboxylate (CAS 941-75-3)
- 2-Ethyl-8,9-dimethoxy-5-((4-methylbenzyl)thio)-[1,2,4]triazolo[1,5-c]quinazoline (CAS 860650-28-8)
- N-(4-Amino-2-methylphenyl)methanesulfonamide (CAS 57165-01-2)
- Isobutyl chloroformate (CAS 543-27-1)
- Zinc, [5,10,15,20-tetrakis(4-ethynylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]-, (SP-4-1)- (CAS 502613-00-5)
- 7-Nitroquinolin-8-amine (CAS 42606-35-9)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com