Ethyl (R)-6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate CAS 1786424-99-4
| CAS No. | 1786424-99-4 |
| Molecular Formula | C17H14BrClFN3O2S |
| Molecular Weight | 458.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl (R)-6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ethyl (R)-6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (CAS 1786424-99-4), molecular formula C17H14BrClFN3O2S and molecular weight 458.73 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, Ethyl (R)-6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 458.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H14BrClFN3O2S |
| Molecular Weight | 458.73 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- Ethyl (R)-6-(bromomethyl)-4-(2-chloro-3-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (CAS 1638652-90-0)
- Di-tert-butyl (7-bromo-6-chloroquinazolin-2-yl)iminodicarbonate (CAS 2641062-28-2)
- Ethyl 6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate (CAS 1092953-02-0)
- Didecyl 3,3'-thiodipropanoate (CAS 4275-40-5)
- Analysis of Pb quality control samples in rice meal (CAS CATO-CQCM100717)
- 2-Amino-2-(4-methoxyphenyl)ethanol (CAS 138713-55-0)
- 5,7-Dimethyl-1H-indole-2-carboxylic acid (CAS 221675-45-2)
- 4-(4-Nitrobenzyl)-7-oxo-2-(trifluoromethyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1135989-39-7)
- 6-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-methylnicotinic acid (CAS 1355200-34-8)
- 1-Fluoro-5-iodonaphthalene (CAS 1261683-97-9)
- 3-Cyclobutylbutyric acid (CAS 1081556-88-8)
- (5-(Difluoromethyl)-2-fluoropyridin-4-yl)methanamine (CAS 1805005-89-3)
- 7-Bromo-3-iodocinnoline (CAS 1956332-51-6)
- Fas C- Terminal Tripeptide (CAS 189109-90-8)
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