4-Amino-1-((2R,3S,4R,5R)-3-chloro-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one CAS 1786426-19-4
| CAS No. | 1786426-19-4 |
| Molecular Formula | C9H11ClFN3O4 |
| Molecular Weight | 279.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Amino-1-((2R,3S,4R,5R)-3-chloro-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 1786426-19-4) is a high-purity analytical reference standard with the molecular formula C9H11ClFN3O4 and a molecular weight of 279.65 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-Amino-1-((2R,3S,4R,5R)-3-chloro-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 279.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Amino-1-((2R,3S,4R,5R)-3-chloro-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11ClFN3O4 |
| Molecular Weight | 279.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
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Recommended Standards
- Methyl 4-(chlorosulfonyl)-3-nitrobenzoate (CAS 162010-78-8)
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- 2-[4-(chlorosulfonyl)-3-nitrophenyl]acetic acid (CAS 1864063-25-1)
- 2-(4-Bromophenyl)-1-(6-methoxypyridin-3-yl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1023474-23-8)
- N-Methyl-2,6-dinitro-4-(trifluoromethyl)aniline (CAS 6574-17-0)
- (2-Nitrophenyl)methanesulfonyl fluoride (CAS 1675732-94-1)
- 1,1'-(5,5-Dihydroxydihydropyrimidine-1,3(2H,4H)-diyl)bis(propan-1-one) (CAS 393056-46-7)
- 5380-87-0 Furfuryl glycidyl ether 2-((2,3-Epoxypropoxy)methyl)furan Furan, 2-((2,3-epoxypropoxy)methyl)- Furan, 2-((oxiranylmethoxy)methyl)- (9CI) 5-17-03-00347 (Beilstein Handbook Reference) BRN 1239147 EINECS 226-372-6 2-((Oxiranylmethoxy)methyl)furan (CAS 5380-87-0)
- 3,5-Bis(cyclohexanecarboxamido)benzoic acid (CAS 337501-82-3)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-fluoropyridine-5-methanol (CAS 1805439-95-5)
- 2,6-Dibromo-4-(hydroxymethyl)phenol (CAS 2316-62-3)
- 2-Chloroethyl Chloromethyl Ether (CAS 1462-33-5)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
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