3-Amino-6-bromopyrazine-2-carboxamide CAS 17890-77-6
| CAS No. | 17890-77-6 |
| Molecular Formula | C5H5BrN4O |
| Molecular Weight | 217.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-6-bromopyrazine-2-carboxamide is closely related to an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-6-bromopyrazine-2-carboxamide (CAS 17890-77-6) is a high-purity analytical reference standard with the molecular formula C5H5BrN4O and a molecular weight of 217.02 g/mol.
The molecular framework of 3-Amino-6-bromopyrazine-2-carboxamide (C5H5BrN4O) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5BrN4O |
| Molecular Weight | 217.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 1000339-23-0 2-AMINO-5-BROMO-4-PYRIDINECARBOXYLIC ACID 2-AMINO-5-BROMOISONICOTINIC ACID 2-AMINO-5-BROMOPYRIDINE-4-CARBOXYLIC ACID BC003478 (CAS 1000339-23-0)
- 6-Amino-3-bromopicolinic acid (CAS 1033201-61-4)
- 3-Amino-6-bromopyridine-2-carboxylic Acid (CAS 1052708-46-9)
- 4-Amino-2-bromonicotinic acid (CAS 1060809-71-3)
- 4-Amino-6-bromopicolinic acid (CAS 1060811-27-9)
- 2-Amino-6-bromoisonicotinic acid (CAS 1060811-29-1)
- 4-Amino-6-bromonicotinic acid (CAS 1060811-30-4)
- 2-Amino-6-bromonicotinic acid (CAS 1196157-51-3)
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