3-Bromo-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one CAS 178946-24-2
| CAS No. | 178946-24-2 |
| Molecular Formula | C6H7BrF3NO |
| Molecular Weight | 246.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one (CAS 178946-24-2), molecular formula C6H7BrF3NO and molecular weight 246.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one (C6H7BrF3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7BrF3NO |
| Molecular Weight | 246.03 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Why CATO?
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