tert-butyl 2-(3-bromo-2-oxopyrrolidin-1-yl)acetate CAS 178946-66-2
| CAS No. | 178946-66-2 |
| Molecular Formula | C10H16BrNO3 |
| Molecular Weight | 278.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 278.14 g/mol gives tert-butyl 2-(3-bromo-2-oxopyrrolidin-1-yl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies tert-butyl 2-(3-bromo-2-oxopyrrolidin-1-yl)acetate (CAS 178946-66-2), a certified reference material (molecular formula C10H16BrNO3, MW 278.14 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H16BrNO3, tert-butyl 2-(3-bromo-2-oxopyrrolidin-1-yl)acetate contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 278.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H16BrNO3 |
| Molecular Weight | 278.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl 3-bromo-3-methyl-2-oxopyrrolidine-1-carboxylate (CAS 171201-54-0)
- Tert-butyl (S)-2-(bromomethyl)-4-oxopyrrolidine-1-carboxylate (CAS 1801748-54-8)
- tert-Butyl 3-bromo-2-oxopiperidine-1-carboxylate (CAS 1707358-29-9)
- 2'-Amino-3'-bromo-3-methyl-[1,1'-biphenyl]-2-ol (CAS 1823590-48-2)
- 3-(Cyclopropylmethyl)-2-hydroxy-N,N-dimethylbenzamide (CAS 1243439-19-1)
- 1-[3-fluoro-4-(methylsulfanyl)phenyl]ethan-1-one (CAS 2968-09-4)
- [6-(4-methylpiperidin-1-yl)pyridin-3-yl]methanamine (CAS 926266-32-2)
- Butane-1,1-diol (CAS 99801-86-2)
- 6-(4-Bromophenyl)morpholin-2-one (CAS 1823362-79-3)
- 2-Bromo-3-cyano-4-fluorobenzenesulfonyl chloride (CAS 1805583-66-7)
- N,N'-Dibenzyl-N'',N'''-bis(propan-2-yl)propanediamide (CAS 197961-02-7)
- N,N-Dimethyl-N-[3,4,5-tricyano-6-(4-methylphenyl)-2-pyridinyl]iminoformamide (CAS 478081-26-4)
- tert-Butyl 3-{[3-(dimethylamino)-2,2-dimethylpropyl]amino}propanoate (CAS 1221342-42-2)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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