Methyl 4-Chloroquinoline-7-carboxylate CAS 178984-69-5
| CAS No. | 178984-69-5 |
| Molecular Formula | C11H8ClNO2 |
| Molecular Weight | 221.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-Chloroquinoline-7-carboxylate.
Methyl 4-Chloroquinoline-7-carboxylate (CAS 178984-69-5), molecular formula C11H8ClNO2 and molecular weight 221.64 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 4-Chloroquinoline-7-carboxylate (C11H8ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 4-Chloroquinoline-7-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO2 |
| Molecular Weight | 221.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 4-Chloroquinoline-2-carboxylate (CAS 114935-92-1)
- Methyl 2-chloroquinoline-5-carboxylate (CAS 1192569-38-2)
- 6-Chloroquinoline-3-carbohydrazide (CAS 1239727-47-9)
- 7-Chloroquinoline-4-carbohydrazide (CAS 13337-46-7)
- Methyl 7-chloroquinoline-4-carboxylate (CAS 13337-76-3)
- Methyl3-chloroquinoline-6-carboxylate (CAS 1357958-20-3)
- Methyl 5-chloroquinoline-3-carboxylate (CAS 1415989-49-9)
- Methyl 4-chloroquinoline-8-carboxylate (CAS 1416440-14-6)
Recommended Standards
- 2-(2-Chloroquinolin-3-yl)acetic acid (CAS 1710643-90-5)
- 4-(4-Chlorobenzylidene)-3-methylisoxazol-5(4H)-one (CAS 17975-47-2)
- 8-Chloro-7-methylquinoline-4-carboxylic acid (CAS 1695872-02-6)
- (E)-N'-(4-chlorobenzylidene)-2-cyanoacetohydrazide (CAS 180793-13-9)
- 1-Methyl-5-((trimethylsilyl)ethynyl)-1H-imidazole (CAS 480439-45-0)
- 5-(4-fluorophenyl)-3-[(2,3,3-trichloroacryloyl)amino]thiophene-2-carboxamide (CAS 648410-18-8)
- 2-Chloro-1,3,2-dioxaphospholane (CAS 822-39-9)
- Rofecoxib-d5 (CAS 544684-93-7)
- 7-(Bromomethyl)-1-methylquinolin-2(1H)-one (CAS 133032-61-8)
- Z-D-Gla(OtBu)2-OH (CAS 2044710-50-9)
- 1-(3-Fluorophenyl)-2-(trifluoromethoxy)ethan-1-one (CAS 1334148-55-8)
- 5-Bromo-2-tritylisoindoline (CAS 405150-03-0)
- 3,4-Dihydro-2H-pyrano[3,2-b]pyridine-3-carboxylic acid (CAS 1516559-81-1)
- Cycloaspeptide A (CAS 109171-13-3)
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