4-(Piperazin-1-yl)pyrimidin-2-amine dihydrochloride CAS 179250-37-4

Purity 97%+In StockPharmaceutical Standards
CAS No.179250-37-4
Molecular FormulaC8H13N5
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Piperazin-1-yl)pyrimidin-2-amine dihydrochloride CAS 179250-37-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 215.69 g/mol gives 4-(Piperazin-1-yl)pyrimidin-2-amine dihydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(Piperazin-1-yl)pyrimidin-2-amine dihydrochloride (CAS 179250-37-4), molecular formula C8H13N5HCl and molecular weight 215.69 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(Piperazin-1-yl)pyrimidin-2-amine dihydrochloride (C8H13N5HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(Piperazin-1-yl)pyrimidin-2-amine dihydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H13N5 2*HCl
Molecular Weight215.69 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2008
Halogen ContentCl-containing
Nitrogen Atoms5

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