2,8-Dimethyl-6-nitro-[1,2,4]triazolo[1,5-a]pyridine CAS 1794153-77-7
| CAS No. | 1794153-77-7 |
| Molecular Formula | C8H8N4O2 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,8-Dimethyl-6-nitro-[1,2,4]triazolo[1,5-a]pyridine is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2,8-Dimethyl-6-nitro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1794153-77-7), a certified reference material (molecular formula C8H8N4O2, MW 192.17 g/mol) for analytical method development and quality control.
2,8-Dimethyl-6-nitro-[1,2,4]triazolo[1,5-a]pyridine (C8H8N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,8-Dimethyl-6-nitro-[1,2,4]triazolo[1,5-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8N4O2 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 4 |
Related Dimethyl Standards
- 4,5-Dimethyl-2-Nitrophenyl Isocyanate (CAS 102561-40-0)
- 2,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 108129-01-7)
- 1,3-Dimethyl-1H-pyrazolo[3,4-d]pyrimidine-4-carboxylic acid (CAS 1095822-32-4)
- 8,9-Dimethyl-9H-purine-6-carboxylic acid (CAS 1095823-07-6)
- 3,7-Dimethyl-6-oxo-6,7-dihydroisoxazolo[5,4-b]pyridine-5-carbaldehyde (CAS 1352534-45-2)
- 2,7-Dimethyl-5-nitro-1,3-benzoxazole (CAS 1441051-52-0)
- 1,5-Dimethyl-1H-pyrazolo[3,4-c]pyridazine-4-carboxylic acid (CAS 2468993-23-7)
- 1,7-Dimethyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione (CAS 66690-78-6)
Recommended Standards
- Methyl 6-hydroxyimidazo[1,2-a]pyridine-3-carboxylate (CAS 1785002-51-8)
- Gefitinib Impurity 4 (CAS 179688-52-9)
- Methyl 7-aminopyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 1784334-86-6)
- 4-Methoxybenzofuran-6-carboxylic acid (CAS 18014-95-4)
- Ethyl (2-oxopiperidin-1-yl)acetate (CAS 22875-63-4)
- 2-((2-Methoxyphenyl)amino)-2-(thiophen-2-yl)acetic acid (CAS 725253-17-8)
- (S)-Benzyl 3-((3-fluoropropyl)amino)pyrrolidine-1-carboxylate (CAS 1363408-37-0)
- (S)-tert-Butyl ((1-(2-aminoacetyl)pyrrolidin-2-yl)methyl)(cyclopropyl)carbamate (CAS 1353994-69-0)
- 1-(5-(3-Methylpiperidin-1-yl)-2-nitrophenyl)ethan-1-one (CAS 923248-99-1)
- 2-Bromo-5-cyano-4-(difluoromethyl)benzoic acid (CAS 1807073-30-8)
- 4-Chloro-1-(4-methoxy-phenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 650628-54-9)
- 1,7,13-Trithia-4,10-diazacyclohexadecan-15-ol (CAS 343372-29-2)
- (R)-1-(4-ethoxyphenyl)propan-1-amine (CAS 856758-62-8)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
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