Prucalopride hydrochloride CAS 179474-80-7
| CAS No. | 179474-80-7 |
| Molecular Formula | C18H26ClN3O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Prucalopride hydrochloride (C18H26ClN3O3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Prucalopride hydrochloride (CAS 179474-80-7) is a high-purity analytical reference standard with the molecular formula C18H26ClN3O3HCl and a molecular weight of 404.33 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H26ClN3O3 HCl |
| Molecular Weight | 404.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Prucalopride Standards
- Prucalopride Impurity 35 (CAS 1098624-57-7)
- Prucalopride Impurity 55 (CAS 1178666-74-4(free base))
- Prucalopride Impurity 23 (CAS 123654-26-2)
- Prucalopride Impurity 7 (CAS 129511-06-4)
- Prucalopride Succinate Impurity 45 (CAS 1352965-19-5)
- Prucalopride Impurity 48 (CAS 137211-63-3)
- Prucalopride Impurity 13 (CAS 137211-64-4)
- Prucalopride Impurity 31 (CAS 137211-64-4（free base）)
Recommended Standards
- 1-(Aminomethyl)cycloheptane-1-carboxylic acid (CAS 1251337-59-3)
- 4-(Dodecyloxy)phthalonitrile (CAS 161082-75-3)
- 2-(6-Bromonaphthalen-2-yl)-5-propyl-1,3,4-oxadiazole (CAS 1133116-07-0)
- 1-Heptyl-1h-imidazol-2-amine (CAS 1179291-45-2)
- 2-(1H-Benzo[d][1,2,3]triazol-1-yl)-2-((ethoxycarbonyl)amino)acetic acid (CAS 168162-19-4)
- 3-methyl-3H-imidazo[4,5-b]pyridine-5-carboxylic acid hydrochloride (CAS 1803605-87-9)
- (5-Cyclohexyl-1,2,4-oxadiazol-3-yl)methanamine (CAS 946702-34-7)
- 6-Bromo-7-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1780873-07-5)
- 2-(3-Bromophenyl)-2,2-difluoroacetic Acid (CAS 885068-76-8)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com