1-(2,2-Difluoroethyl)-4-nitro-1H-pyrazole-5-carboxylic acid CAS 1795275-24-9
| CAS No. | 1795275-24-9 |
| Molecular Formula | C6H5F2N3O4 |
| Molecular Weight | 221.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2,2-Difluoroethyl)-4-nitro-1H-pyrazole-5-carboxylic acid (CAS 1795275-24-9) is a high-purity analytical reference standard with the molecular formula C6H5F2N3O4 and a molecular weight of 221.12 g/mol.
1-(2,2-Difluoroethyl)-4-nitro-1H-pyrazole-5-carboxylic acid (C6H5F2N3O4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)-4-nitro-1H-pyrazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5F2N3O4 |
| Molecular Weight | 221.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)-4-nitro-1H-pyrazole-3-carboxylic acid (CAS 1006442-59-6)
- 1-(2,2-Difluoroethyl)-5-nitro-1H-pyrazole-3-carboxylic acid (CAS 1328640-66-9)
- 1-(2,2-Difluoroethyl)-3-nitro-1h-pyrazole-5-carboxylic acid (CAS 1328640-79-4)
- 1-(2,2-Difluoroethyl)-3-nitro-1H-pyrazole-4-carboxylic acid (CAS 1798678-71-3)
- Methyl 2-(1-(2,2-difluoroethyl)piperidin-4-yl)acetate (CAS 1245772-02-4)
- 2-(4-(1,1-Difluoroethyl)piperidin-1-yl)propanoic acid (CAS 1949815-71-7)
- Ethyl 1-(2,2-difluoroethyl)piperidine-3-carboxylate (CAS 937603-28-6)
- 1-(2,2-Difluoroethyl)-4-nitro-1H-pyrazole-3-carboxamide (CAS 1787881-28-0)
Recommended Standards
- 4,4,5,5-Tetramethyl-2-(m-tolyl)-1,3,2-dioxaborolane-d3 (CAS 1592865-91-2)
- 2-(3-(Difluoromethyl)-4-nitro-1H-pyrazol-1-yl)acetic acid (CAS 1795503-05-7)
- 2-(5-Bromothiazol-2-yl)propan-1-amine (CAS 1511255-62-1)
- 2-(5-Bromothiazol-2-yl)-N-methylethan-1-amine (CAS 1508076-82-1)
- [2-[(3-Carboxypropanoyl)oxy]ethyl]trimethylazanium iodide (CAS 14720-92-4)
- (3-Methyl-5-nitrophenyl)methanamine (CAS 1261881-26-8)
- 1,2-dioxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-8-carboxylic acid (CAS 1384429-51-9)
- 3-(Aminomethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one (CAS 1425045-12-0)
- 2,3-Dibromo-6-(difluoromethoxy)toluene (CAS 1806305-36-1)
- n-Cyclopropyl-2-(3,5-dimethyl-4-nitro-1h-pyrazol-1-yl)acetamide (CAS 956265-77-3)
- (1S,3R)-3-Aminocyclohexane-1-carboxylic acid (CAS 81131-40-0)
- 1-(4-Oxo-7-(p-tolyl)-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-N-(pyridin-2-ylmethyl)piperidine-3-carboxamide (CAS 1242879-14-6)
- 2,6-Dichloro-3-methoxyaniline (CAS 55285-43-3)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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