1-(5-Chloro-2-methoxyphenyl)-3-(2-ethoxy-4,6-dimethylpyrimidin-5-yl)urea CAS 1795299-70-5
| CAS No. | 1795299-70-5 |
| Molecular Formula | C16H19ClN4O3 |
| Molecular Weight | 350.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(5-Chloro-2-methoxyphenyl)-3-(2-ethoxy-4,6-dimethylpyrimidin-5-yl)urea is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(5-Chloro-2-methoxyphenyl)-3-(2-ethoxy-4,6-dimethylpyrimidin-5-yl)urea (CAS 1795299-70-5), a certified reference material (molecular formula C16H19ClN4O3, MW 350.80 g/mol) for analytical method development and quality control.
The molecular framework of 1-(5-Chloro-2-methoxyphenyl)-3-(2-ethoxy-4,6-dimethylpyrimidin-5-yl)urea (C16H19ClN4O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(5-Chloro-2-methoxyphenyl)-3-(2-ethoxy-4,6-dimethylpyrimidin-5-yl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19ClN4O3 |
| Molecular Weight | 350.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- methyl 7-amino-1,2,3,4-tetrahydroisoquinoline-2-carboxylate (CAS 1448046-09-0)
- 5-(Bromomethyl)-1,2-difluoro-3-(trifluoromethyl)benzene (CAS 239079-92-6)
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- 4-Nitro-2-(phenylamino)benzoic acid (CAS 49551-01-1)
- Trimethyl-d9-sulfoxonium Iodide (CAS 23726-00-3)
- 5-(4,5-Dihydro-1H-imidazol-2-yl)pyrazin-2-amine (CAS 710323-24-3)
- 9,10-Dioxo-9,10-dihydroanthracene-1,8-dicarbonitrile (CAS 90866-50-5)
- 3-(pyrazin-2-yl)-4,5-dihydro-1,2,4-oxadiazol-5-one (CAS 114347-13-6)
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