Benzoyl-DL-leucine CAS 17966-67-5
| CAS No. | 17966-67-5 |
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Benzoyl-DL-leucine.
Benzoyl-DL-leucine (CAS 17966-67-5), molecular formula C13H17NO3 and molecular weight 235.28 g/mol, is a CATO reference standard with documented purity and traceability.
Benzoyl-DL-leucine (C13H17NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Benzoyl-DL-leucine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Benzoyl Standards
- N-benzoyl-N-isobutylglycine (CAS 1267678-47-6)
- N-Benzoyl-L-leucine (CAS 1466-83-7)
- 3-benzoyl-2-methyl-1H-indole (CAS 26211-73-4)
- Benzoyl-l-isoleucine (CAS 36578-01-5)
- N-Benzoyl-L-norleucine (CAS 54430-46-5)
- cis-1-Benzoyl-4-hydroxy-L-proline (CAS 129512-75-0)
- 1-Benzoyl-4-hydroxypyrrolidine-2-carboxylic acid (CAS 1301738-43-1)
- 5-Benzoyl-2H-indol-2-one (CAS 51135-39-8)
Recommended Standards
- WX390 Impurity 2 (CAS 212517-19-6)
- Ac-Phe-OEt (CAS 2361-96-8)
- Evocalcet impurity 60 (CAS 247034-96-4)
- (1Z)-n'-hydroxy-2-(4-pyridin-2-ylpiperazin-1-yl)ethanimidamide (CAS 1016786-03-0)
- N-[(2Z,5Z)-1-Methyl-5-({3-[2-nitro-4-(trifluoromethyl)phenoxy]phenyl}methylidene)-4-oxoimidazolidin-2-ylidene]acetamide (CAS 866154-71-4)
- 6-Nitro-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine (CAS 1105189-59-0)
- 4-Methyl-3H-[1,2,3]triazolo[4,5-c]pyridine (CAS 27582-17-8)
- Pitavastatin Impurity 85 (CAS CATO-C4X-103785)
- 2-((2-Morpholinoethyl)amino)ethanol dihydrochloride (CAS 34750-64-6)
- 6-tert-butyl-4-chloro-1-isopropyl-pyrazolo[3,4-d]pyrimidine (CAS 2868363-04-4)
- 1-(Isoquinolin-5-yl)propan-1-one (CAS 1053656-01-1)
- 4-(2-(Isopropylsulfonyl)phenyl)-1H-pyrrole-3-carbonitrile (CAS 87388-34-9)
- 1-(2-Bromoethoxy)-2-nitrobenzene (CAS 18800-37-8)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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