N-(2-(Thiophen-3-yl)ethyl)-2-(trifluoromethoxy)benzenesulfonamide CAS 1797317-52-2
| CAS No. | 1797317-52-2 |
| Molecular Formula | C13H12F3NO3S2 |
| Molecular Weight | 351.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(2-(Thiophen-3-yl)ethyl)-2-(trifluoromethoxy)benzenesulfonamide (CAS 1797317-52-2), molecular formula C13H12F3NO3S2 and molecular weight 351.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2-(Thiophen-3-yl)ethyl)-2-(trifluoromethoxy)benzenesulfonamide (C13H12F3NO3S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(2-(Thiophen-3-yl)ethyl)-2-(trifluoromethoxy)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12F3NO3S2 |
| Molecular Weight | 351.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related N Standards
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Recommended Standards
- 9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(((R)-tetrahydro-2H-pyran-2-yl)amino)-1H-purin-6(9H)-one (CAS 163088-95-7)
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- N-(2-(Furan-2-carbonyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)-1-methyl-1H-1,2,3-triazole-4-carboxamide (CAS 1448132-09-9)
- ((2R,3S,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl pentanoate (CAS 65926-31-0)
- 4-Mercaptobenzene-1,2-diol (CAS 27320-22-5)
- 3-[(4-Bromophenyl)sulfanyl]-2-phenylquinoline (CAS 477886-48-9)
- 4,6-Dimethyl-5-nitro-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 89977-22-0)
- Ethyl 2-(2-chloroacetamido)-5-(cyanosulfanyl)-4-phenylthiophene-3-carboxylate (CAS 726151-90-2)
- 6-Chloroquinoline-4-carbohydrazide (CAS 41874-23-1)
- 3-Vinylpyridin-2-amine (CAS 102000-72-6)
- 1-phenyl-5-(pyridin-3-yl)-1H-pyrazole-3-carboxylic acid hydrochloride (CAS 1172372-17-6)
- 6-Bromo-2-cyclopropyl-5-methylbenzo[d]oxazole (CAS 1267224-21-4)
- 3,3′,4,4′-Tetrachloroazobenzene (CAS 14047-09-7)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
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