1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane CAS 17977-72-9

Purity 97%+In StockPharmaceutical Standards
CAS No.17977-72-9
Molecular FormulaC18H28O2Si3
Molecular Weight360.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane CAS 17977-72-9 chemical structure

Description

CATO supplies 1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane (CAS 17977-72-9), a certified reference material (molecular formula C18H28O2Si3, MW 360.67 g/mol) for analytical method development and quality control.

The molecular framework of 1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane (C18H28O2Si3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H28O2Si3
Molecular Weight360.67 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962

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