| CAS No. | 17977-72-9 |
| Molecular Formula | C18H28O2Si3 |
| Molecular Weight | 360.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
CATO supplies 1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane (CAS 17977-72-9), a certified reference material (molecular formula C18H28O2Si3, MW 360.67 g/mol) for analytical method development and quality control.
The molecular framework of 1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane (C18H28O2Si3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,1,3,3,5,5-Hexamethyl-1,5-diphenyltrisiloxane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C18H28O2Si3 |
| Molecular Weight | 360.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |