Aripiprazole Impurity 57 CAS 1797983-65-3
| CAS No. | 1797983-65-3 |
| Molecular Formula | C23H27Cl2N3O2 |
| Molecular Weight | 448.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Aripiprazole Impurity 57 (CAS 1797983-65-3), a pharmacopoeial impurity reference standard (molecular formula C23H27Cl2N3O2, MW 448.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Aripiprazole Impurity 57 (C23H27Cl2N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 448.39 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Aripiprazole Impurity 57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27Cl2N3O2 |
| Molecular Weight | 448.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Aripiprazole Standards
- Aripiprazole (CAS 129722-12-9)
- Aripiprazole Impurity 44 (CAS 203395-78-2)
- Aripiprazole Impurity 93 (CAS CATO-C4X-100893)
- Aripiprazole 3,4-Dichloro Analog (CAS 203395-75-9)
- Aripiprazole Impurity 15 (CAS CATO-C4X-100815)
- Aripiprazole Quinolinediol Impurity (CAS 1391054-74-2)
- Aripiprazole EP Impurity E (CAS 129722-25-4)
- Aripiprazole Impurity 4 (CAS 1424858-02-5)
Recommended Standards
- Bicalutamide Impurity 30 (CAS CATO-C4X-101330)
- Ethyl 2-methyl-5-oxo-6-{2-[3-(trifluoromethyl)benzoyloxy]ethyl}-5,6-dihydro-1,6-naphthyridine-3-carboxylate (CAS 338406-15-8)
- (E)-6-(p-tolylthio)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime (CAS 339022-85-4)
- 2-(4-Amino-2-butoxypyridin-3-yl)-4-bromo-N,N-diisopropylbenzamide (CAS 1058129-83-1)
- Benidipine Impurity 44 (CAS CATO-C4X-112044)
- Avanafil Impurity 31 (CAS CATO-C4X-111831)
- Resmetirom impurity 94 (CAS CATO-C4X-291294)
- 3-Chloro-1-(4-methoxyphenyl)-4-(m-tolylamino)-1H-pyrrole-2,5-dione (CAS 61892-19-1)
- 1-Methylsilinan-1-yl trifluoromethanesulfonate (CAS 2412687-28-4)
- Suvorexant Impurity 15 (CAS 1001401-62-2)
- (3S,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one (CAS 82598-88-7)
- (2Z)-2-{[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-4-(methylsulfanyl)-3-oxobutanenitrile (CAS 1164480-54-9)
- 6-Bromo-8-methoxyquinazolin-4(3H)-one (CAS 1616828-53-5)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com