5-Iodo-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione CAS 17993-69-0
| CAS No. | 17993-69-0 |
| Molecular Formula | C14H18ClN3S |
| Molecular Weight | 295.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Iodo-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 17993-69-0) is a high-purity analytical reference standard with the molecular formula C14H18ClN3S and a molecular weight of 295.83 g/mol.
The molecular framework of 5-Iodo-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (C14H18ClN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18ClN3S |
| Molecular Weight | 295.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2'-Chloro-N-cyclopentyl-7'H-spiro[cyclobutane-1,6'-thieno[3,2-d]pyrimidin]-4'-amine (CAS 1422354-57-1)
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- (R)-1-(2,4-dibromophenyl)ethan-1-amine (CAS 1344955-45-8)
- 4-(2-Fluorophenyl)-1H-indole-3-carbaldehyde (CAS 1214346-09-4)
- 7-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-oxo-2,3,5,6,7,8-hexahydro-[1,2,4]triazolo[4,3-a]pyrazine-6-carboxylic acid (CAS 2137493-56-0)
- (S)-Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate (CAS 212557-00-1)
- Fezolinetant Impurity 17 (CAS CATO-C4X-327017)
- 4,4'-(3,4-Dimethylfuran-2,5-diyl)bis(2-methoxyphenol) (CAS 10035-27-5)
- 2-(3-Methoxybenzoyl)pyridine (CAS 55030-49-4)
- 7-(4-Chlorophenyl)-2-(4-(2,5-dimethylphenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1226426-96-5)
- Ethylenediaminetetraacetic Acid Disodium Cobalt Salt Hydrate (CAS 68867-22-1)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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