4-CHLORO-2-(3-FLUOROPYRIDIN-2-YL)-5-ISOPROPYLPYRIMIDINE CAS 1801335-68-1
| CAS No. | 1801335-68-1 |
| Molecular Formula | C12H11ClFN3 |
| Molecular Weight | 251.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-CHLORO-2-(3-FLUOROPYRIDIN-2-YL)-5-ISOPROPYLPYRIMIDINE is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-CHLORO-2-(3-FLUOROPYRIDIN-2-YL)-5-ISOPROPYLPYRIMIDINE (CAS 1801335-68-1), molecular formula C12H11ClFN3 and molecular weight 251.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-CHLORO-2-(3-FLUOROPYRIDIN-2-YL)-5-ISOPROPYLPYRIMIDINE (C12H11ClFN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11ClFN3 |
| Molecular Weight | 251.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related CHLORO Standards
- 4-(4-Chloro-2-fluorophenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine (CAS 1010902-77-8)
- 4-(5-Chloro-2-fluorophenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine (CAS 1010913-03-7)
- 4-(3-Chloro-2-fluorophenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine (CAS 1189749-62-9)
- 4-(3-Chloro-4-fluorophenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 1189749-85-6)
- 4-Chloro-2-(methylsulfanyl)pyrido[3,2:4,5]furo-[3,2-d]pyrimidine (CAS 1198475-41-0)
- 6-Chloro-N-(4-fluorophenethyl)pyrimidin-4-amine (CAS 1292632-69-9)
- 2-Chloro-4,5-dimethoxybenzenesulfonamide (CAS 1342859-02-2)
- 4-Chloro-2-(3-fluoropyridin-2-yl)-5-isopropylpyrimidine (CAS 2119574-84-2)
Recommended Standards
- 5-(Dimethylcarbamoyl)-4-methylfuran-3-sulfonyl chloride (CAS 1503428-64-5)
- 3-Chlorobenzo[b]thieno[3,4-f][1,4]oxazepin-10(9H)-one (CAS 70438-17-4)
- 5-(Acetamidomethyl)-1-methyl-1h-pyrazole-4-sulfonyl chloride (CAS 1365939-89-4)
- 4-Chloro-N-(4-fluorophenyl)-5,6-dimethylpyrimidin-2-amine (CAS 199463-20-2)
- 1-(Propan-2-yl)imidazolidine-2,4,5-trione (CAS 40408-39-7)
- tert-Butyl (R)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoate (CAS 1393721-12-4)
- 1-(4-((4-Chlorophenyl)thio)-3-nitrobenzyl)piperidine (CAS 477869-36-6)
- 4-(methylthio)-3-(trifluoromethyl)aniline 4-methylsulfanyl-3-(trifluoromethyl)aniline 63094-56-4 A834212 (CAS 63094-56-4)
- 5,5',5''-(Benzene-1,3,5-triyl)tris(pyridin-2-amine) (CAS 2757085-59-7)
- 2-(2-Phenyl-1H-imidazol-1-yl)acetic acid (CAS 842958-44-5)
- Methyl 1-Methyl-5-[4-(trifluoromethoxy)phenyl]pyrrole-2-carboxylate (CAS 2006276-88-4)
- (+)-cis-Whiskey lactone (CAS 105015-53-0)
- (2S,3S)-3-(Methoxymethyl)-2-methylmorpholine hydrochloride (CAS 2791475-73-3)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com