2-Amino-N-butyl-5-chlorobenzamide CAS 18014-57-8
| CAS No. | 18014-57-8 |
| Molecular Formula | C11H15ClN2O |
| Molecular Weight | 226.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Amino-N-butyl-5-chlorobenzamide (CAS 18014-57-8) is a high-purity analytical reference standard with the molecular formula C11H15ClN2O and a molecular weight of 226.70 g/mol.
The molecular framework of 2-Amino-N-butyl-5-chlorobenzamide (C11H15ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15ClN2O |
| Molecular Weight | 226.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- N-(5-Amino-2-chlorophenyl)-3-methylbutanamide (CAS 1082128-62-8)
- 2-Amino-N-(1-(3-chlorophenyl)ethyl)-N-methylacetamide (CAS 1179056-83-7)
- 2-Amino-N-(3-chlorobenzyl)-N-ethylacetamide (CAS 1184265-17-5)
- 2-Amino-N-(2-chlorobenzyl)-N-ethylacetamide (CAS 1184563-92-5)
- (R)-(3-amino-4-chloro-2-(pyrrolidin-2-yl)phenyl)methanol (CAS 1213964-54-5)
- 4-Amino-N-(tert-butyl)-2-chlorobenzamide (CAS 128742-22-3)
- (2S)-2-amino-N-(1-(3-chlorophenyl)ethyl)propanamide (CAS 1290219-51-0)
- (S)-2-amino-N-(2-chlorobenzyl)-N-methylpropanamide (CAS 1307201-83-7)
Recommended Standards
- 2-(7-Chloro-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)ethan-1-amine (CAS 1785406-58-7)
- 1-(2-Chloro-5-methoxyphenyl)piperazine (CAS 180698-24-2)
- 3-Chloro-6-isopropyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2(1H)-one (CAS 1779123-08-8)
- 3-(Tert-Butyl)-5-(chloromethyl)-2-hydroxybenzaldehyde (CAS 183017-88-1)
- N-(4-Methoxybenzyl)naphthalen-1-amine (CAS 356536-86-2)
- 4-Hydroxyphenethylanisate (CAS 87932-34-1)
- 2-Methylpyrimidine-5-carboxylic acid hydrate (CAS 1314670-28-4)
- 2-{4-[(2,4-dioxo-1,3-thiazolidin-5-yl)amino]phenyl}acetonitrile (CAS 1214063-87-2)
- Isopropyl (5-chloro-2-methylphenyl)carbamate (CAS 2621-68-3)
- N-Ethyl-4-chlorobenzylamine (CAS 69957-83-1)
- N-Cyclobutyl-2-methyl-1H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 71149-50-3)
- 6-(Aminomethyl)-4-cyclopropoxy-N,N-dimethylnicotinamide (CAS 1243444-24-7)
- 5-((4-Bromo-2-chlorophenoxy)methyl)furan-2-carbohydrazide (CAS 832738-18-8)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com