Tert-butyl 2-(3-nitrophenyl)acetate CAS 180150-74-7
| CAS No. | 180150-74-7 |
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Tert-butyl 2-(3-nitrophenyl)acetate (CAS 180150-74-7), a certified reference material (molecular formula C12H15NO4, MW 237.25 g/mol) for analytical method development and quality control.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Tert-butyl 2-(3-nitrophenyl)acetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]acetic acid (CAS 17969-24-3)
- Aminooxy-PEG3-acid (CAS 1807540-79-9)
- PD 151746 (CAS 179461-52-0)
- (Z)-3-(5-Fluoro-1H-indol-3-yl)-2-mercaptoacrylic acid (CAS 181765-30-0)
- 3-Benzamido-N-cyclopropylthiophene-2-carboxamide (CAS 439120-50-0)
- 1-(Difluoromethoxy)-3-naphthol (CAS 1261600-48-9)
- (S)-2-Amino-N-cyclopropyl-3-methyl-N-(4-methylbenzyl)butanamide (CAS 1307224-35-6)
- (R)-2-(Pyrrolidin-1-yl)propan-1-amine hydrochloride (CAS 2763741-24-6)
- 1-ethyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (CAS 199933-01-2)
- 3-Bromo-2-pyrrolidinomethyl benzophenone (CAS 898774-44-2)
- 3-[(4-methylphenyl)amino]propanethioamide (CAS 1049874-17-0)
- 2',4'-Dichloro-7'H-spiro[cyclobutane-1,6'-thieno[3,2-d]pyrimidine] (CAS 1422354-56-0)
- (4-Butoxy-3,5-difluorophenyl)(methyl)sulfane (CAS 1443303-14-7)
- Anorexigenic Peptide (CAS 69275-10-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com