7-​Chloro-​1,​5-​dihydro-​5-​[2-​(1-​methylethyl)​phenyl]​-4,​1-benzothiazepin-​2(3H)​-​one CAS 1802013-08-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1802013-08-6
Molecular FormulaC18H18ClNOS
Molecular Weight331.86 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-​Chloro-​1,​5-​dihydro-​5-​[2-​(1-​methylethyl)​phenyl]​-4,​1-benzothiazepin-​2(3H)​-​one CAS 1802013-08-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-​Chloro-​1,​5-​dihydro-​5-​[2-​(1-​methylethyl)​phenyl]​-4,​1-benzothiazepin-​2(3H)​-​one.

7-​Chloro-​1,​5-​dihydro-​5-​[2-​(1-​methylethyl)​phenyl]​-4,​1-benzothiazepin-​2(3H)​-​one (CAS 1802013-08-6) is a high-purity analytical reference standard with the molecular formula C18H18ClNOS and a molecular weight of 331.86 g/mol.

The molecular framework of 7-​Chloro-​1,​5-​dihydro-​5-​[2-​(1-​methylethyl)​phenyl]​-4,​1-benzothiazepin-​2(3H)​-​one (C18H18ClNOS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H18ClNOS
Molecular Weight331.86 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

Related Chloro Standards

Recommended Standards

Why CATO?