tert-Butyl N-(3-methylpyridin-4-yl)carbamate CAS 180253-65-0
| CAS No. | 180253-65-0 |
| Molecular Formula | C11H16N2O2 |
| Molecular Weight | 208.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
tert-Butyl N-(3-methylpyridin-4-yl)carbamate (CAS 180253-65-0) is a high-purity analytical reference standard with the molecular formula C11H16N2O2 and a molecular weight of 208.26 g/mol.
The molecular framework of tert-Butyl N-(3-methylpyridin-4-yl)carbamate (C11H16N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O2 |
| Molecular Weight | 208.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 2 |
Recommended Standards
- (R)-6-(6-methylpyridin-2-yloxy)-1,4-oxazepane (CAS 1795777-36-4)
- tert-Butyl (4-methylpyridin-3-yl)carbamate (CAS 180253-66-1)
- Ethyl 3-amino-4-(dimethylamino)benzoate (CAS 178469-07-3)
- 3-amino-1-(1-ethyl-1H-pyrazol-5-yl)piperidin-2-one (CAS 1803580-59-7)
- 3-[4-(3-methoxyphenyl)piperazin-1-yl]propan-1-amine (CAS 20529-24-2)
- 2-(5-Methylpyrimidin-2-yl)acetonitrile (CAS 1408196-51-9)
- 2-Chloro-1-methyl-6-nitro-1H-benzo[d]imidazole (CAS 15965-67-0)
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- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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