Solifenacin EP Impurity I CAS 180272-28-0
| CAS No. | 180272-28-0 |
| Molecular Formula | C23H26N2O3 |
| Molecular Weight | 378.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Solifenacin EP Impurity I (CAS 180272-28-0), a pharmacopoeial impurity reference standard (molecular formula C23H26N2O3, MW 378.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Solifenacin EP Impurity I (C23H26N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 378.46 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H26N2O3 |
| Molecular Weight | 378.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 2 |
Related Solifenacin Standards
- Solifenacin Related Compound 29 (CAS 861998-77-8)
- Solifenacin Impurity 29 (CAS CATO-C4X-105329)
- Solifenacin Impurity 37 (CAS CATO-C4X-105337)
- Solifenacin Impurity 6 (CAS 1956436-64-8)
- Solifenacin Impurity 8 (CAS CATO-C4X-10538)
- Solifenacin Impurity 38 (CAS 605696-10-4)
- Solifenacin (CAS 242478-37-1)
- Solifenacin EP Impurity H (CAS 732228-02-3)
Recommended Standards
- Glasdegib D4 (CAS 321744-26-7(Unlabelled))
- P3JW662TWA 92623-83-1 Pravadoline Pravadoline [INN] Methanone, (4-methoxyphenyl)(2-methyl-1-(2-(4-morpholinyl)ethyl)-1H-indol-3-yl)- Pravadolina [INN-Spanish] Pravadolinum [INN-Latin] Pravadolina Pravadolinum UNII-P3JW662TWA WIN 48098 (CAS 92623-83-1)
- Z-Leu-Ile-OH (CAS 42537-96-2)
- Tetrabenz[a,c,h,j]anthracene (CAS 215-11-2)
- 7-ACCA Impurity 1 (CAS CATO-C4X-23131)
- Selexipag Impurity 39 (CAS CATO-C4X-196139)
- Mirabegron Impurity 57 (CAS 2184223-32-1)
- 2-Deoxy-5-[3-[[[(3,6-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-1-propynyl]uridine 5-(Tetrahydrogen Triphosphate) (CAS 137993-59-0)
- N-(4-aminophenyl)butyramide (CAS 116884-02-7)
- (1-(2-Aminophenyl)pyrrolidin-3-yl)methanol (CAS 1378860-45-7)
- (R)-3-Bromo-4,4-dimethyldihydrofuran-2(3H)-one (CAS 1217724-84-9)
- Bis(2,2'-bipyridine)-(5-isothiocyanato-phenanthroline)ruthenium bis(hexafluorophosphate) (CAS 288399-07-5)
- Hexahydrohippuric acid (CAS 32377-88-1)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com