2-(pyridin-4-yloxy)benzoic acid hydrochloride CAS 1803567-54-5
| CAS No. | 1803567-54-5 |
| Molecular Formula | C12H9NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(pyridin-4-yloxy)benzoic acid hydrochloride.
2-(pyridin-4-yloxy)benzoic acid hydrochloride (CAS 1803567-54-5) is a high-purity analytical reference standard with the molecular formula C12H9NO3HCl and a molecular weight of 251.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(pyridin-4-yloxy)benzoic acid hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9NO3 HCl |
| Molecular Weight | 251.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related pyridin Standards
- 3-[(E)-2-(Pyridin-3-yl)ethenyl]-1,2-dihydroquinoxalin-2-one (CAS 1000169-10-7)
- 2-(pyridin-2-ylsulfanyl)acetic acid (CAS 10002-29-6)
- 4-(Pyridin-3-yloxy)benzenesulfonic acid (CAS 1000340-09-9)
- 2-(2-Oxo-2-(pyridin-4-yl)ethylidene)thiazolidin-4-one (CAS 1000932-15-9)
- 2-[2-oxo-2-(pyridin-3-yl)ethylidene]-1,3-thiazolidin-4-one (CAS 1000932-62-6)
- N-(pyridin-3-ylmethyl)sulfamide (CAS 1000933-31-2)
- Ethyl 1-(2-pyridin-2-ylethyl)piperidine-4-carboxylate (CAS 1000941-29-6)
- 1-Methyl-4-(pyridin-2-ylmethyl)piperazine (CAS 100158-57-4)
Recommended Standards
- 1,4,5,8-Tetraamino-2,7-bis(4-methoxyphenoxy)anthracene-9,10-dione (CAS 88600-81-1)
- 6-Chloro-3-iodo-2-phenylimidazo[1,2-b]pyridazine (CAS 1023697-90-6)
- 3-Allyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 103951-13-9)
- Vildagliptin Impurity 79 (CAS CATO-C4X-110079)
- 2,6-Dimethyl-3-nitropyridin-4-ol (CAS 13603-45-7)
- 2-(Cyclohexylmethyl)-4-isopropoxyphenol (CAS 1243287-48-0)
- Trospium Impurity 9 (CAS CATO-C4X-20389)
- 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-5-amine (CAS 1306603-61-1)
- 4-(3,3,3-Trifluoropropyl)aniline (CAS 1236410-18-6)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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