2-(1,2,5,6-tetrahydropyridin-3-yl)pyridine dihydrochloride CAS 1803585-18-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1,2,5,6-tetrahydropyridin-3-yl)pyridine dihydrochloride.

2-(1,2,5,6-tetrahydropyridin-3-yl)pyridine dihydrochloride (CAS 1803585-18-3), molecular formula C10H12N2HCl and molecular weight 196.68 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(1,2,5,6-tetrahydropyridin-3-yl)pyridine dihydrochloride (C10H12N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(1,2,5,6-tetrahydropyridin-3-yl)pyridine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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