1-(3-fluoropyridin-2-yl)-3-oxa-1-azaspiro[4.4]nonan-2-one CAS 1803587-86-1
| CAS No. | 1803587-86-1 |
| Molecular Formula | C12H13FN2O2 |
| Molecular Weight | 236.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-fluoropyridin-2-yl)-3-oxa-1-azaspiro[4.4]nonan-2-one.
1-(3-fluoropyridin-2-yl)-3-oxa-1-azaspiro[4.4]nonan-2-one (CAS 1803587-86-1) is a high-purity analytical reference standard with the molecular formula C12H13FN2O2 and a molecular weight of 236.24 g/mol.
1-(3-fluoropyridin-2-yl)-3-oxa-1-azaspiro[4.4]nonan-2-one (C12H13FN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-fluoropyridin-2-yl)-3-oxa-1-azaspiro[4.4]nonan-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13FN2O2 |
| Molecular Weight | 236.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- Bis((5-fluoropyridin-3-yl)methyl)amine (CAS 1073372-18-5)
- N-[(6-Fluoropyridin-2-yl)amino]-2-(1H-1,2,4-triazol-1-yl)ethanimidamide (CAS 477852-46-3)
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Recommended Standards
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- 1-[4-(4-hydroxyphenyl)-1,2,3,6-tetrahydropyridin-1-yl]ethan-1-one (CAS 203438-46-4)
- Tert-butyl ((1-hydroxycyclohexyl)methyl)carbamate (CAS 885954-83-6)
- Tert-butyl n-{9-azabicyclo[3.3.1]nonan-3-yl}carbamate (CAS 1208530-70-4)
- N1-(2-Aminoethyl)-N1-phenylethane-1,2-diamine (CAS 4182-45-0)
- 2-(4-Chlorophenyl)-2-(4-methyl-1-piperazinyl)ethylamine (CAS 919724-53-1)
- 3-Bromo-2-(difluoromethyl)-5-methylpyridin-4-amine (CAS 1806831-00-4)
- Ethyl (1R,2R)-2-([1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylate (CAS 1052650-70-0)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
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