1-(azidomethyl)-2,5-difluoro-4-(trifluoromethyl)benzene CAS 1803589-86-7
| CAS No. | 1803589-86-7 |
| Molecular Formula | C8H4F5N3 |
| Molecular Weight | 237.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(azidomethyl)-2,5-difluoro-4-(trifluoromethyl)benzene (CAS 1803589-86-7), molecular formula C8H4F5N3 and molecular weight 237.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 1-(azidomethyl)-2,5-difluoro-4-(trifluoromethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1-(azidomethyl)-2,5-difluoro-4-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4F5N3 |
| Molecular Weight | 237.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related azidomethyl Standards
- 2-(azidomethyl)benzene-1-sulfonyl chloride (CAS 1365252-90-9)
- 2-(Azidomethyl)-1-benzoylpyrrolidine (CAS 1785762-74-4)
- [2-(Azidomethyl)-3-pyridinyl]-1H-imidazol-1-yl-methanone (CAS 1612756-29-2)
- 4-[3-(Azidomethyl)phenyl]-2-hydroxy-4-oxo-2-butenoic Acid (CAS 544467-07-4)
- 2-(Azidomethyl)-3-bromo-6-chloropyridine (CAS 2083629-39-2)
- 1858256-78-6 Methyl 5-(azidomethyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate MFCD29034964 (CAS 1858256-78-6)
- 1-[2-(azidomethyl)-5-fluoro-2-methyl-3H-benzofuran-7-yl]ethanone (CAS 2556808-01-4)
- methyl 4-(azidomethyl)bicyclo[2.2.2]octane-1-carboxylate (CAS 2167955-11-3)
Recommended Standards
- 2-chloro-1-(4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone (CAS 1553611-49-6)
- 2-Difluoromethoxy-6-(trifluoromethyl)benzonitrile (CAS 1803824-14-7)
- 5-[(trifluoroacetamido)methyl]furan-2-carboxylic acid (CAS 1538710-07-4)
- 2-Difluoromethoxy-3-(trifluoromethyl)benzonitrile (CAS 1803832-79-2)
- (2'-Chloro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1373767-70-4)
- 1-(4-chlorophenyl)-3-[imino(nitroamino)methyl]thiourea (CAS 204188-36-3)
- Diethyl 6-amino-1-benzamido-2-oxo-1,2-dihydropyridine-3,5-dicarboxylate (CAS 146255-43-8)
- tert-Butyl methyl(2-(2-(methylamino)ethoxy)ethyl)carbamate (CAS 1465601-43-7)
- 4,4,5,5-Tetramethyl-2-(7-methylbenzofuran-2-yl)-1,3,2-dioxaborolane (CAS 1072812-57-7)
- 1-Benzyl-5-(aminomethyl)piperidin-2-one (CAS 1272756-11-2)
- Methyl 5-hydroxy-2-(trifluoromethyl)benzoate (CAS 1261852-24-7)
- (R)-3-hydroxy-1-methylpiperidin-2-one (CAS 614754-30-2)
- (2R,4R)-4-amino-8-azaspiro[4.5]Decan-2-ol dihydrochloride (CAS 1801767-44-1)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com