ethyl 4-chloro-8-methoxy-3-methylquinoline-2-carboxylate CAS 1803592-06-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1803592-06-4
Molecular FormulaC14H14ClNO3
Molecular Weight279.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

ethyl 4-chloro-8-methoxy-3-methylquinoline-2-carboxylate CAS 1803592-06-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 279.72 g/mol gives ethyl 4-chloro-8-methoxy-3-methylquinoline-2-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

ethyl 4-chloro-8-methoxy-3-methylquinoline-2-carboxylate (CAS 1803592-06-4), molecular formula C14H14ClNO3 and molecular weight 279.72 g/mol, is a CATO reference standard with documented purity and traceability.

ethyl 4-chloro-8-methoxy-3-methylquinoline-2-carboxylate (C14H14ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H14ClNO3
Molecular Weight279.72 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentCl-containing
Nitrogen Atoms1

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