3-methyl-5-(piperazin-1-yl)-1,2-thiazole-4-carbonitrile CAS 1803592-90-6
| CAS No. | 1803592-90-6 |
| Molecular Formula | C9H12N4S |
| Molecular Weight | 208.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-methyl-5-(piperazin-1-yl)-1,2-thiazole-4-carbonitrile (CAS 1803592-90-6), molecular formula C9H12N4S and molecular weight 208.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-methyl-5-(piperazin-1-yl)-1,2-thiazole-4-carbonitrile (C9H12N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-methyl-5-(piperazin-1-yl)-1,2-thiazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12N4S |
| Molecular Weight | 208.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related methyl Standards
- 4-(Piperazin-1-ylmethyl)benzene-1,2-diol (CAS 1178067-02-1)
- 2-(2-Piperazin-1-ylethyl)pyridazin-3(2H)-one (CAS 1341994-60-2)
- 4-(Piperazin-1-ylmethyl)benzene-1,3-diol (CAS 917201-65-1)
- 6-Ethyl-2-(piperazin-1-yl)pyrimidin-4(1H)-one (CAS 502133-37-1)
- 6-(Piperazin-1-yl)pyridazine-3-carboxylic acid (CAS 1304876-43-4)
- 5-(Piperazin-1-yl)pyrazine-2-carboxylic acid (CAS 1339131-26-8)
- 6-(Piperazin-1-yl)pyridazine-4-carboxylic acid (CAS 1706442-50-3)
- 2-(Piperazin-1-yl)pyrimidine-5-carboxylic acid (CAS 944905-05-9)
Recommended Standards
- (3R,5S)-1-benzyl-5-fluoropiperidin-3-amine (CAS 1792184-90-7)
- 2-[(piperidine-1-sulfonyl)amino]ethan-1-ol (CAS 181762-02-7)
- 1-[(4-Fluorophenyl)methyl]-3-methylpiperazine (CAS 178624-87-8)
- (5S)-5-methyl-3-(phenylthio)dihydrofuran-2(3H)-one (CAS 184435-75-4)
- 1,7-Dimethyl-3-(2-oxopropyl)oxazolo[2,3-f]purine-2,4(1H,3H)-dione (CAS 899997-80-9)
- 5-Nitropyridin-2-amine (CAS 67476-67-9)
- n-(2-Hydroxyphenyl)piperidine-4-carboxamide (CAS 885524-82-3)
- methyl 2-(cyclopropylamino)-1,3-thiazole-5-carboxylate (CAS 1354957-74-6)
- 3-(2-Chloro-6-nitrophenyl)-2-oxopropanoic acid (CAS 36892-19-0)
- 3,4,5-Trichlorobenzenesulfonamide (CAS 150729-70-7)
- 3-chloro-6-methyl-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1019033-24-9)
- 2-[(Dimethylamino)methyl]-4-fluoroaniline (CAS 1153396-50-9)
- 2-Methoxy-6-nitrobenzaldehyde (CAS 19689-88-4)
- Semaglutide Impurity 145 (CAS CATO-C4X-2226145)
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