4-(2,6-Difluorophenyl)piperidin-4-ol hydrochloride CAS 1803595-27-8
| CAS No. | 1803595-27-8 |
| Molecular Formula | C11H13F2NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(2,6-Difluorophenyl)piperidin-4-ol hydrochloride (CAS 1803595-27-8), molecular formula C11H13F2NOHCl and molecular weight 249.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-(2,6-Difluorophenyl)piperidin-4-ol hydrochloride is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 249.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-(2,6-Difluorophenyl)piperidin-4-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13F2NO HCl |
| Molecular Weight | 249.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenyl Standards
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- Methyl 2-(2,3-difluorophenyl)-2-hydroxyacetate (CAS 1001159-03-0)
- 2-(2,4-Difluorophenyl)cyclopropan-1-amine (CAS 1001318-18-8)
- (4R)-4-(2,4-difluorophenyl)pyrrolidine-3-carbonitrile (CAS 1002728-74-6)
- N-(2,5-Difluorophenyl)-3-methylbenzamide (CAS 1002813-62-8)
- 4-(3,5-Difluorophenyl)piperidinehydrochloride (CAS 1004618-89-6)
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Recommended Standards
- N-(4-butylphenyl)-4-nitrobenzamide (CAS 99338-13-3)
- N-(4-amino-2-bromophenyl)acetamide (CAS 436090-22-1)
- methyl (3R)-3-amino-3-(3-bromophenyl)propanoate (CAS 845958-74-9)
- (R)-N-(4-Acetylthiazol-2-yl)-2-aminopropanamide (CAS 1344915-09-8)
- 4-Phenyloxazol-5-amine (CAS 856989-55-4)
- n-(1-Cyclopropylethyl)-3-phenylpropan-1-amine (CAS 1038278-65-7)
- 4-(1-(2-(Dimethylamino)ethyl)-1h-pyrazol-4-yl)benzoic acid (CAS 1206970-25-3)
- Ethyl 2-(3-(4-chlorophenyl)ureido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 202804-58-8)
- 3-Ethyl-2-piperazinone hydrate (CAS 1214065-31-2)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
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