4-Fluoro-2-((tetrahydro-2H-pyran-4-yl)oxy)aniline hydrochloride CAS 1803604-07-0
| CAS No. | 1803604-07-0 |
| Molecular Formula | C11H14FNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Fluoro-2-((tetrahydro-2H-pyran-4-yl)oxy)aniline hydrochloride.
CATO supplies 4-Fluoro-2-((tetrahydro-2H-pyran-4-yl)oxy)aniline hydrochloride (CAS 1803604-07-0), a certified reference material (molecular formula C11H14FNO2HCl, MW 247.69 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-2-((tetrahydro-2H-pyran-4-yl)oxy)aniline hydrochloride (C11H14FNO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14FNO2 HCl |
| Molecular Weight | 247.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
- 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)aniline (CAS 1000053-56-4)
- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
- Ethyl 4-fluoro-3-ethoxybenzoate (CAS 1000207-63-5)
- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 1-(5-Fluoro-2-methylphenyl)pyrrolidine (CAS 1000339-32-1)
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- Ethyl cinnoline-3-carboxylate (CAS 67080-45-9)
- 2-(4-Methylphenyl)-4,5-dihydro-1h-imidazole (CAS 13623-58-0)
- 2,3,3-Trimethyl-5-(phenylsulfonyl)-3H-indole (CAS 55203-59-3)
- 6-(2-Chlorophenoxy)-5-fluoro-4(3H)-pyrimidinone (CAS 519002-09-6)
- 2-(Difluoromethyl)-4-fluoro-5-hydroxy-3-nitropyridine (CAS 1805580-12-4)
- N-methyl-1-(6-methylpyridazin-3-yl)piperidin-3-amine (CAS 1247729-18-5)
- Methyl 2-(3-(aminomethyl)phenyl)acetate hydrochloride (CAS 197792-60-2)
- N-(2,4-dichloro-5-isopropoxyphenyl)-2-((2-(methylamino)-2-oxoethyl)sulfonyl)acetamide (CAS 341964-56-5)
- 2-(p-Tolyl)-4H-pyrazolo[1,5-a]indole (CAS 141235-71-4)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com