3-(2,2-difluoroethyl)morpholine CAS 1803607-74-0
| CAS No. | 1803607-74-0 |
| Molecular Formula | C6H11F2NO |
| Molecular Weight | 151.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2,2-difluoroethyl)morpholine is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(2,2-difluoroethyl)morpholine (CAS 1803607-74-0) is a high-purity analytical reference standard with the molecular formula C6H11F2NO and a molecular weight of 151.15 g/mol.
3-(2,2-difluoroethyl)morpholine (C6H11F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2,2-difluoroethyl)morpholine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H11F2NO |
| Molecular Weight | 151.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluoroethyl Standards
- 1-(2,2-Difluoroethyl)pyrrolidin-3-ol (CAS 1342568-51-7)
- [1-(2,2-Difluoroethyl)azetidin-3-yl]methanol (CAS 1491346-76-9)
- (3S)-1-(2,2-Difluoroethyl)pyrrolidin-3-ol (CAS 1568026-19-6)
- 2-(1,1-difluoroethyl)morpholine (CAS 1784677-56-0)
- (3S)-3-(2,2-difluoroethyl)morpholine (CAS 2380646-23-9)
- [(2S)-1-(2,2-difluoroethyl)azetidin-2-yl]methanol (CAS 2820536-96-5)
- [1-(2,2-difluoroethyl)azetidin-2-yl]methanol (CAS 2295981-67-6)
- 4-(1,1-Difluoroethyl)-3-hydroxyazetidin-2-one (CAS 1824387-82-7)
Recommended Standards
- 4,4-difluoro-1-methylpiperidin-3-ol (CAS 1785484-23-2)
- rel-(1R,2R)-2-(Difluoromethoxy)cyclopentan-1-amine (CAS 1807941-11-2)
- trans-2-(difluoromethoxy)cyclopentan-1-amine (CAS 1820574-36-4)
- (4,4-Difluoro-1-methylpyrrolidin-3-yl)methanol (CAS 1784503-73-6)
- 5-Phosphoryl-(3-amino-3-deoxyguanylyl)-(3-5)-3-amino-3-deoxycytidine (CAS 109679-54-1)
- {6-[4-(2-Chloro-pyrimidin-4-yl)-phenyl]-4-trifluoromethyl-pyridin-2-yl}-dimethyl-amine (CAS 1311278-60-0)
- 2-(3,4,5-Trimethoxyphenyl)thiazolidine-4-carboxylic acid (CAS 72678-94-5)
- 1-(2-Hydroxyethyl)piperidine-4-carbonitrile (CAS 21168-73-0)
- 5-Chloro-6-ethoxynaphthalene-2-sulfonyl chloride (CAS 1394820-11-1)
- N'-(2,4-dihydroxybenzylidene)isonicotinohydrazide (CAS 3477-69-8)
- 3-Azetidinomethyl-3,4,5-trifluorobenzophenone (CAS 898772-30-0)
- 4-(Difluoromethyl)-3-fluorobenzonitrile (CAS 206201-67-4)
- (2S,3S)-3-Amino-2-(((benzyloxy)carbonyl)amino)butanoic acid (CAS 687629-90-9)
- Cyclopeptide-5 (CAS 197172-76-2)
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