2-Amino-6-(difluoromethyl)-4-fluoropyridine-3-sulfonamide CAS 1803697-33-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1803697-33-7
Molecular FormulaC6H6F3N3O2S
Molecular Weight241.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-6-(difluoromethyl)-4-fluoropyridine-3-sulfonamide CAS 1803697-33-7 chemical structure

Description

The occurrence of 2-Amino-6-(difluoromethyl)-4-fluoropyridine-3-sulfonamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Amino-6-(difluoromethyl)-4-fluoropyridine-3-sulfonamide (CAS 1803697-33-7) is a high-purity analytical reference standard with the molecular formula C6H6F3N3O2S and a molecular weight of 241.19 g/mol.

The molecular framework of 2-Amino-6-(difluoromethyl)-4-fluoropyridine-3-sulfonamide (C6H6F3N3O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Amino-6-(difluoromethyl)-4-fluoropyridine-3-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H6F3N3O2S
Molecular Weight241.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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