1-(7-(Difluoromethoxy)benzo[d]oxazol-2-yl)ethanone CAS 1804192-22-0
| CAS No. | 1804192-22-0 |
| Molecular Formula | C10H7F2NO3 |
| Molecular Weight | 227.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(7-(Difluoromethoxy)benzo[d]oxazol-2-yl)ethanone (CAS 1804192-22-0), molecular formula C10H7F2NO3 and molecular weight 227.16 g/mol, is a CATO reference standard with documented purity and traceability.
1-(7-(Difluoromethoxy)benzo[d]oxazol-2-yl)ethanone (C10H7F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-(7-(Difluoromethoxy)benzo[d]oxazol-2-yl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F2NO3 |
| Molecular Weight | 227.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethoxy Standards
- 5-(Difluoromethoxy)-1H-indole-3-carboxylic acid (CAS 1135935-39-5)
- 1-(2-(Difluoromethoxy)benzo[d]oxazol-4-yl)ethanone (CAS 1804191-75-0)
- 1-(5-(Difluoromethoxy)benzo[d]oxazol-2-yl)ethanone (CAS 1806429-69-5)
- 1-(4-(Difluoromethoxy)benzo[d]oxazol-2-yl)ethanone (CAS 1806573-06-7)
- 4-(Difluoromethoxy)-1h-indole-2-carboxylic acid (CAS 885524-95-8)
- 5-[3-(difluoromethoxy)phenyl]-1,3,4-oxadiazol-2-amine (CAS 1039899-32-5)
- 4-(3-(Difluoromethoxy)phenyl)-4H-1,2,4-triazol-3-ol (CAS 1858255-65-8)
- 2-Difluoromethoxy-4-(trifluoromethyl)aniline (CAS 1803781-52-3)
Recommended Standards
- 2-Cyano-5-(difluoromethoxy)-4-methylbenzoic acid (CAS 1804929-43-8)
- 2-(Difluoromethyl)benzo[d]oxazole-7-acetic acid (CAS 1804079-81-9)
- 2-(4-(Difluoromethyl)benzo[d]oxazol-2-yl)acetic acid (CAS 1806303-61-6)
- 2-(Difluoromethyl)benzo[d]oxazole-6-acetic acid (CAS 1803741-44-7)
- N-methyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carboxamide (CAS 893902-85-7)
- 3-Chloro-5-fluoro-2-methoxybenzyl alcohol (CAS 1785513-23-6)
- (S)-Benzyl 2-(iodomethyl)pyrrolidine-1-carboxylate (CAS 172885-53-9)
- Paclobutrazol Impurity 2 (CAS 66345-53-7)
- 8-Oxabicyclo[3.2.1]octan-3-amine (CAS 911826-55-6)
- 5-Bromo-8-fluoro-2,3-dihydroquinolin-4(1H)-one (CAS 1388026-46-7)
- tert-Butyl 17-bromoheptadecanoate (CAS 2428400-70-6)
- 3-Fluoro-4-(N-morpholino)phenol (CAS 1171917-53-5)
- 3,5-Dimethylisoxazol-4-ol (CAS 13054-62-1)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com