2-(4-(Difluoromethyl)-6-hydroxy-5-(trifluoromethoxy)pyridin-2-yl)acetonitrile CAS 1804360-63-1
| CAS No. | 1804360-63-1 |
| Molecular Formula | C9H5F5N2O2 |
| Molecular Weight | 268.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(4-(Difluoromethyl)-6-hydroxy-5-(trifluoromethoxy)pyridin-2-yl)acetonitrile (CAS 1804360-63-1), a certified reference material (molecular formula C9H5F5N2O2, MW 268.14 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(4-(Difluoromethyl)-6-hydroxy-5-(trifluoromethoxy)pyridin-2-yl)acetonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-(Difluoromethyl)-6-hydroxy-5-(trifluoromethoxy)pyridin-2-yl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5F5N2O2 |
| Molecular Weight | 268.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-3-hydroxy-5-(trifluoromethoxy)pyridine-6-acetonitrile (CAS 1803959-84-3)
- 2-(4-(Difluoromethyl)-2-hydroxy-6-(trifluoromethoxy)pyridin-3-yl)acetonitrile (CAS 1804347-30-5)
- 2-(Difluoromethyl)-3-hydroxy-5-(trifluoromethoxy)pyridine-4-acetonitrile (CAS 1804477-96-0)
- 2-(Difluoromethyl)-5-hydroxy-3-(trifluoromethoxy)pyridine-4-acetonitrile (CAS 1804478-02-1)
- 2-(4-(Difluoromethyl)-2-hydroxy-5-(trifluoromethoxy)pyridin-3-yl)acetonitrile (CAS 1804478-36-1)
- 2-(Difluoromethyl)-4-hydroxy-3-(trifluoromethoxy)pyridine-6-acetonitrile (CAS 1804725-55-0)
- 2-(2-(Difluoromethyl)-6-hydroxy-3-(trifluoromethoxy)pyridin-4-yl)acetonitrile (CAS 1804796-73-3)
- 2-(Difluoromethyl)-4-hydroxy-6-(trifluoromethoxy)pyridine-3-acetonitrile (CAS 1804839-36-8)
Recommended Standards
- 1-(5-(2,5-Dichlorophenyl)-1-methyl-1H-pyrrol-2-yl)ethanone (CAS 1706437-78-6)
- 4-iodo-2,2,6,6-tetramethyl-tetrahydropyran (CAS 1638768-38-3)
- 1-(Benzo[d][1,3]dioxol-5-yl)-2,2,3,3,3-pentafluoropropan-1-one (CAS 1443354-07-1)
- 1-(7,8-Dichloro-4-methylquinolin-2-yl)propan-2-one (CAS 1437455-74-7)
- H-D-Cys(Bzl)-OH (CAS 23032-53-3)
- 4-(Benzo[d]thiazol-2-yl)-1H-1,2,3-triazol-5(2H)-one (CAS 204771-20-0)
- 3-Chloro-4-ethynylaniline (CAS 80690-65-9)
- Potassium trans-2,3-dihydroxysuccinate (CAS 4504-81-8)
- 4,4'-(Anthracene-9,10-diyl)dibenzoic acid (CAS 42824-53-3)
- 2-(5-(tert-Butyl)-2-methyl-1H-indol-3-yl)acetic acid (CAS 383131-81-5)
- 3-Chloro-2-phenylfuro[2,3-b]quinoxaline (CAS 88051-13-2)
- 2-Amino-5-(1-ethyl-1h-1,2,4-triazol-5-yl)phenol (CAS 1247436-61-8)
- 2-(2-Methoxyphenyl)-1-(7-phenyl-1,4-thiazepan-4-yl)ethan-1-one (CAS 1797572-69-0)
- Anorexigenic Peptide (CAS 69275-10-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com