4-Cyano-2-(difluoromethyl)-6-iodopyridine-3-sulfonyl chloride CAS 1804380-45-7
| CAS No. | 1804380-45-7 |
| Molecular Formula | C7H2ClF2IN2O2S |
| Molecular Weight | 378.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Cyano-2-(difluoromethyl)-6-iodopyridine-3-sulfonyl chloride (C7H2ClF2IN2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Cyano-2-(difluoromethyl)-6-iodopyridine-3-sulfonyl chloride (CAS 1804380-45-7), molecular formula C7H2ClF2IN2O2S and molecular weight 378.52 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Cyano-2-(difluoromethyl)-6-iodopyridine-3-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H2ClF2IN2O2S |
| Molecular Weight | 378.52 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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