2,3-Dibromo-5-fluorophenacyl chloride CAS 1804418-48-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1804418-48-1
Molecular FormulaC8H4Br2ClFO
Molecular Weight330.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,3-Dibromo-5-fluorophenacyl chloride CAS 1804418-48-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,3-Dibromo-5-fluorophenacyl chloride.

2,3-Dibromo-5-fluorophenacyl chloride (CAS 1804418-48-1) is a high-purity analytical reference standard with the molecular formula C8H4Br2ClFO and a molecular weight of 330.38 g/mol.

2,3-Dibromo-5-fluorophenacyl chloride (C8H4Br2ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H4Br2ClFO
Molecular Weight330.38 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl/Br-containing

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