2-(Difluoromethyl)-4-fluoro-3-hydroxy-6-iodopyridine CAS 1804424-45-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1804424-45-0
Molecular FormulaC6H3F3INO
Molecular Weight288.99 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-4-fluoro-3-hydroxy-6-iodopyridine CAS 1804424-45-0 chemical structure

Description

2-(Difluoromethyl)-4-fluoro-3-hydroxy-6-iodopyridine (CAS 1804424-45-0), molecular formula C6H3F3INO and molecular weight 288.99 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-(Difluoromethyl)-4-fluoro-3-hydroxy-6-iodopyridine (C6H3F3INO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 288.99 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Difluoromethyl)-4-fluoro-3-hydroxy-6-iodopyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H3F3INO
Molecular Weight288.99 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/I-containing
Nitrogen Atoms1

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