6-Bromo-5-(difluoromethyl)-4-nitronicotinaldehyde CAS 1804432-03-8
| CAS No. | 1804432-03-8 |
| Molecular Formula | C7H3BrF2N2O3 |
| Molecular Weight | 281.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Bromo-5-(difluoromethyl)-4-nitronicotinaldehyde (C7H3BrF2N2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-Bromo-5-(difluoromethyl)-4-nitronicotinaldehyde (CAS 1804432-03-8) is a high-purity analytical reference standard with the molecular formula C7H3BrF2N2O3 and a molecular weight of 281.01 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Bromo-5-(difluoromethyl)-4-nitronicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3BrF2N2O3 |
| Molecular Weight | 281.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-3-(difluoromethyl)-5-nitropicolinaldehyde (CAS 1804978-64-0)
- 6-Bromo-5-(difluoromethyl)-3-nitropicolinaldehyde (CAS 1805166-14-6)
- 4-Bromo-2-(difluoromethyl)-6-nitronicotinaldehyde (CAS 1805166-55-5)
- 4-Bromo-2-(difluoromethyl)-5-nitronicotinaldehyde (CAS 1805358-64-8)
- 2-Bromo-6-(difluoromethyl)-3-nitroisonicotinaldehyde (CAS 1805443-81-5)
- 4-Bromo-5-(difluoromethyl)-2-nitronicotinaldehyde (CAS 1805935-14-1)
- 6-Bromo-5-(difluoromethyl)-4-nitropicolinaldehyde (CAS 1806858-09-2)
- 6-Bromo-3-(difluoromethyl)-5-nitropicolinaldehyde (CAS 1806858-11-6)
Recommended Standards
- 2,3-Dichloro-6-(difluoromethoxy)benzotrifluoride (CAS 1803831-47-1)
- 2,3-Dichloro-5-(difluoromethoxy)benzotrifluoride (CAS 1804882-88-9)
- 2,6-Dichloro-3-(difluoromethoxy)benzotrifluoride (CAS 1803788-96-6)
- 2,4-Dichloro-5-(difluoromethoxy)benzotrifluoride (CAS 1804883-02-0)
- 8-Chloro-3,5-dihydrospiro[benzo[b]azepine-4,2'-[1,3]dioxolan]-2(1H)-one (CAS 2677030-99-6)
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