6-Bromo-5-(difluoromethyl)nicotinonitrile CAS 1804440-17-2
| CAS No. | 1804440-17-2 |
| Molecular Formula | C7H3BrF2N2 |
| Molecular Weight | 233.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-5-(difluoromethyl)nicotinonitrile.
CATO supplies 6-Bromo-5-(difluoromethyl)nicotinonitrile (CAS 1804440-17-2), a certified reference material (molecular formula C7H3BrF2N2, MW 233.01 g/mol) for analytical method development and quality control.
The molecular framework of 6-Bromo-5-(difluoromethyl)nicotinonitrile (C7H3BrF2N2) is characterized by a nitrile group, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Bromo-5-(difluoromethyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3BrF2N2 |
| Molecular Weight | 233.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 3-Bromo-5,6-difluoro-1H-indazole (CAS 1017781-94-0)
- 2-Bromo-5,6-difluoro-1H-benzo[d]imidazole (CAS 1332576-98-3)
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Recommended Standards
- 2-(4-Iodo-1H-pyrazol-3-yl)acetonitrile (CAS 1707359-71-4)
- 4-Iodonicotinaldehyde (CAS 169614-46-4)
- 3-Iodopicolinaldehyde (CAS 169614-45-3)
- 6-Bromo-5-(difluoromethyl)picolinonitrile (CAS 1806011-20-0)
- tert-Butyl 3-benzylimidazolidine-1-carboxylate (CAS 623943-75-9)
- 2-(4-(2,2-Dicyanovinyl)phenoxy)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 333778-05-5)
- (2S)-2-amino-3-{pyrido[2,3-b]pyrazin-7-yl}propanoic acid (CAS 1306728-61-9)
- 3-(1-Amino-2-methylpropan-2-yl)pyrrolidin-3-ol (CAS 1505024-57-6)
- (1R,2R)-2-(tert-butoxycarbonyl)cyclobutane-1-carboxylic acid (CAS 2089246-48-8)
- 4-((2-(Hydroxymethyl)phenyl)dimethylsilyl)benzonitrile (CAS 947515-74-4)
- 2-Hydroxy-4-iodonicotinaldehyde (CAS 726206-53-7)
- 4-Methoxy-N-(5-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)-2,3-dihydro-1H-inden-2-yl)benzenesulfonamide (CAS 114149-42-7)
- Diquafosol Impurity 19 (CAS 2050-92-2)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
Why CATO?
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