3,6-Diamino-5-(difluoromethyl)picolinic acid CAS 1804444-85-6
| CAS No. | 1804444-85-6 |
| Molecular Formula | C7H7F2N3O2 |
| Molecular Weight | 203.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 203.15 g/mol gives 3,6-Diamino-5-(difluoromethyl)picolinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3,6-Diamino-5-(difluoromethyl)picolinic acid (CAS 1804444-85-6), a certified reference material (molecular formula C7H7F2N3O2, MW 203.15 g/mol) for analytical method development and quality control.
Structurally, 3,6-Diamino-5-(difluoromethyl)picolinic acid (C7H7F2N3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 203.15 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,6-Diamino-5-(difluoromethyl)picolinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7F2N3O2 |
| Molecular Weight | 203.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Diamino Standards
- 2,3-Diamino-5-(difluoromethyl)pyridine-6-carboxylic acid (CAS 1804444-80-1)
- 4,6-Diamino-3-(difluoromethyl)picolinic acid (CAS 1804697-11-7)
- 2,3-Diamino-5-(difluoromethyl)pyridine-4-carboxylic acid (CAS 1805236-48-9)
- 4,6-Diamino-5-(difluoromethyl)nicotinic acid (CAS 1805961-81-2)
- 5,6-Diamino-4-(difluoromethyl)picolinic acid (CAS 1806783-85-6)
- 2,3-Diamino-4-(difluoromethyl)pyridine-5-carboxylic acid (CAS 1806807-63-5)
- 2,6-Diamino-4-(difluoromethyl)nicotinic acid (CAS 1806865-52-0)
- 5,6-Diamino-2-(difluoromethyl)nicotinic acid (CAS 1806868-20-1)
Recommended Standards
- 6-Amino-5-(difluoromethyl)-3-hydroxypicolinamide (CAS 1804514-79-1)
- 4-Amino-5-(difluoromethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 1803673-85-9)
- 6-Amino-3-(difluoromethyl)-5-hydroxypicolinamide (CAS 1804515-00-1)
- 5-Amino-3-(difluoromethyl)-2-oxo-1,2-dihydropyridine-4-carboxamide (CAS 1803673-82-6)
- Ethyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate (CAS 1596348-32-1)
- Iloperidone Impurity 19 (CAS 54771-60-7)
- (2-((1h-1,2,4-Triazol-1-yl)methyl)phenyl)methanamine (CAS 159148-84-2)
- tert-Butyl 4-(5-iodopyridin-3-yl)piperidine-1-carboxylate (CAS 1523618-23-6)
- 3-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-6-carboxylic acid (CAS 144888-66-4)
- 1-Chloro-1-(4-methoxyphenyl)propan-2-one (CAS 23022-81-3)
- 4-(Aminomethyl)-1-cyclopentylpyrrolidin-2-one (CAS 893750-56-6)
- (2-Fluoro-3-iodo-6-methoxyphenyl)(methyl)sulfane (CAS 2635937-43-6)
- 4-Bromo-2-chloro-5-fluorobenzenesulfonamide (CAS 1208075-72-2)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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