2-Amino-6-cyano-4-(difluoromethyl)nicotinic acid CAS 1804485-16-2
| CAS No. | 1804485-16-2 |
| Molecular Formula | C8H5F2N3O2 |
| Molecular Weight | 213.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Amino-6-cyano-4-(difluoromethyl)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2-Amino-6-cyano-4-(difluoromethyl)nicotinic acid (CAS 1804485-16-2), a certified reference material (molecular formula C8H5F2N3O2, MW 213.14 g/mol) for analytical method development and quality control.
2-Amino-6-cyano-4-(difluoromethyl)nicotinic acid (C8H5F2N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F2N3O2 |
| Molecular Weight | 213.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 6-Amino-5-cyano-2-(difluoromethyl)nicotinic acid (CAS 1805060-88-1)
- 6-Amino-5-cyano-4-(difluoromethyl)nicotinic acid (CAS 1805109-77-6)
- 2-Amino-5-cyano-3-(difluoromethyl)isonicotinic acid (CAS 1805339-92-7)
- 4-Amino-6-cyano-5-(difluoromethyl)picolinic acid (CAS 1805348-07-5)
- 2-Amino-3-cyano-6-(difluoromethyl)isonicotinic acid (CAS 1805930-38-4)
- 4-Amino-2-cyano-5-(difluoromethyl)nicotinic acid (CAS 1805935-38-9)
- 4-Amino-6-cyano-3-(difluoromethyl)picolinic acid (CAS 1806813-44-4)
- 4-Amino-5-cyano-3-(difluoromethyl)picolinic acid (CAS 1806813-83-1)
Recommended Standards
- 2-(Difluoromethoxy)benzo[d]oxazole-4-carboxaldehyde (CAS 1804191-40-9)
- 6-(Difluoromethyl)-3-methyl-4-nitropicolinonitrile (CAS 1804733-14-9)
- 2-(Difluoromethyl)-4-nitropyridine-6-acetonitrile (CAS 1803693-81-3)
- 1-(difluoromethyl)-3-nitro-1H-indazole (CAS 1803599-67-8)
- (3-Fluorocyclohexyl)methanesulfonyl chloride (CAS 1779746-74-5)
- (4-Cyanomethyl)-cyclohexyl-carbamic acid tert-butyl ester (CAS 1403764-79-3)
- 2,6-dichloro-4-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]pyridine (CAS 680215-80-9)
- endo-N,9-Dimethyl-9-azabicyclo[3.3.1]nonan-3-amine (CAS 123259-33-6)
- 1,2,3,4-Tetrabromobutane (CAS 1529-68-6)
- 4,6-dichloro-2-(difluoromethyl)pyrimidine (CAS 1816289-02-7)
- 3-(2-Fluorophenyl)-N-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 246021-96-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com