2-Amino-5-(difluoromethyl)-3-fluoroisonicotinaldehyde CAS 1804485-82-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-5-(difluoromethyl)-3-fluoroisonicotinaldehyde.

2-Amino-5-(difluoromethyl)-3-fluoroisonicotinaldehyde (CAS 1804485-82-2) is a high-purity analytical reference standard with the molecular formula C7H5F3N2O and a molecular weight of 190.12 g/mol.

The molecular framework of 2-Amino-5-(difluoromethyl)-3-fluoroisonicotinaldehyde (C7H5F3N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Amino-5-(difluoromethyl)-3-fluoroisonicotinaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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