2-Amino-5-(difluoromethyl)-4-iodonicotinic acid CAS 1804513-99-2
| CAS No. | 1804513-99-2 |
| Molecular Formula | C7H5F2IN2O2 |
| Molecular Weight | 314.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Amino-5-(difluoromethyl)-4-iodonicotinic acid (C7H5F2IN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 314.03 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Amino-5-(difluoromethyl)-4-iodonicotinic acid (CAS 1804513-99-2) is a high-purity analytical reference standard with the molecular formula C7H5F2IN2O2 and a molecular weight of 314.03 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-5-(difluoromethyl)-4-iodonicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5F2IN2O2 |
| Molecular Weight | 314.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 6-Amino-5-(difluoromethyl)-4-iodopicolinic acid (CAS 1804513-93-6)
- 6-Amino-5-(difluoromethyl)-4-iodonicotinic acid (CAS 1805137-88-5)
- 4-Amino-3-(difluoromethyl)-5-iodopicolinic acid (CAS 1805138-33-3)
- 4-Amino-6-(difluoromethyl)-5-iodonicotinic acid (CAS 1805961-50-5)
- 6-Amino-5-(difluoromethyl)-3-iodopicolinic acid (CAS 1806789-19-4)
- 6-Amino-2-(difluoromethyl)-5-iodonicotinic acid (CAS 1806789-57-0)
- 2-Amino-5-(difluoromethyl)-3-iodoisonicotinic acid (CAS 1806810-06-9)
- 4-Amino-5-(difluoromethyl)-6-iodopicolinic acid (CAS 1806810-34-3)
Recommended Standards
- 2-(Difluoromethyl)-3-iodo-5-methyl-4-nitropyridine (CAS 1804865-71-1)
- 3-(Difluoromethoxy)-2-iodobenzoic acid (CAS 2383082-26-4)
- 4-(Difluoromethyl)-2-iodo-3-methyl-5-nitropyridine (CAS 1804865-91-5)
- 1,8-Bis(bromomethyl)naphthalene (CAS 2025-95-8)
- Methyl 4-butoxy-1H-indole-2-carboxylate (CAS 887360-12-5)
- Methyl 4-(benzyloxy)-3-fluorobenzoate (CAS 2379322-19-5)
- 5-Amino-N-ethylnicotinamide (CAS 1415343-06-4)
- Tris(4-bromophenyl)phosphane (CAS 29949-81-3)
- 4-(4-Formyl-2-pyrimidinyl)phenyl 4-fluorobenzenecarboxylate (CAS 477870-91-0)
- 2-Isobutyl-4-methylthiazole (CAS 61323-24-8)
- 3-(3-Methylcyclohexyl)propan-1-ol (CAS 109942-21-4)
- 5-Octyl-1H-indole (CAS 1221257-24-4)
- 3,3'-Diamino-[1,1'-biphenyl]-4,4'-dicarboxylic acid (CAS 1799740-97-8)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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