3,5-Dichloro-2-(difluoromethoxy)benzodifluoride CAS 1804516-17-3
| CAS No. | 1804516-17-3 |
| Molecular Formula | C8H4Cl2F4O |
| Molecular Weight | 263.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3,5-Dichloro-2-(difluoromethoxy)benzodifluoride (CAS 1804516-17-3), molecular formula C8H4Cl2F4O and molecular weight 263.02 g/mol, is a CATO reference standard with documented purity and traceability.
3,5-Dichloro-2-(difluoromethoxy)benzodifluoride (C8H4Cl2F4O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2F4O |
| Molecular Weight | 263.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- 2,4-Dichloro-3-(difluoromethoxy)benzodifluoride (CAS 1803712-59-5)
- 4,5-Dichloro-2-(difluoromethoxy)benzodifluoride (CAS 1803712-62-0)
- 3,4-Dichloro-2-(difluoromethoxy)benzodifluoride (CAS 1803787-83-8)
- 2,6-Dichloro-3-(difluoromethoxy)benzodifluoride (CAS 1803787-92-9)
- 2,6-Dichloro-4-(difluoromethoxy)benzodifluoride (CAS 1803817-84-6)
- 2,3-Dichloro-6-(difluoromethoxy)benzodifluoride (CAS 1803830-91-2)
- 2,3-Dichloro-4-(difluoromethoxy)benzodifluoride (CAS 1804516-12-8)
- 2,5-Dichloro-4-(difluoromethoxy)benzodifluoride (CAS 1805124-43-9)
Recommended Standards
- 5-Bromo-3-fluoro-2-nitrobenzamide (CAS 1805030-52-7)
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- 2-Bromo-6-fluoro-3-nitrobenzamide (CAS 1805593-34-3)
- 3,4-Dichloro-5-(difluoromethoxy)benzodifluoride (CAS 1806275-51-3)
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