6-Bromo-5-(difluoromethyl)-4-hydroxypicolinic acid CAS 1804652-86-5
| CAS No. | 1804652-86-5 |
| Molecular Formula | C7H4BrF2NO3 |
| Molecular Weight | 268.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 268.01 g/mol gives 6-Bromo-5-(difluoromethyl)-4-hydroxypicolinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Bromo-5-(difluoromethyl)-4-hydroxypicolinic acid (CAS 1804652-86-5), molecular formula C7H4BrF2NO3 and molecular weight 268.01 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Bromo-5-(difluoromethyl)-4-hydroxypicolinic acid (C7H4BrF2NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 268.01 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Bromo-5-(difluoromethyl)-4-hydroxypicolinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4BrF2NO3 |
| Molecular Weight | 268.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-1-(difluoromethoxy)-3-nitrobenzene (CAS 1174315-54-8)
- 1-Bromo-3-(difluoromethoxy)-5-nitrobenzene (CAS 1261441-47-7)
- 4-Bromo-1-(difluoromethoxy)-2-nitrobenzene (CAS 1261552-41-3)
- 4-Bromo-2-(difluoromethoxy)-1-nitrobenzene (CAS 1261849-33-5)
- 3-Bromo-2-fluoro-5-(trifluoromethyl)benzonitrile (CAS 133013-32-8)
- 6-Bromo-2-fluoro-3-(trifluoromethyl)benzonitrile (CAS 1802370-84-8)
- 4-Bromo-5-(difluoromethyl)-3-hydroxypicolinic acid (CAS 1804652-97-8)
- 2-Bromo-5-(difluoromethyl)-4-hydroxynicotinic acid (CAS 1804844-39-0)
Recommended Standards
- 2-Bromo-4-(difluoromethyl)-6-hydroxynicotinic acid (CAS 1805241-83-1)
- 4-Bromo-3-(difluoromethyl)-5-hydroxypyridine-2-carboxylic acid (CAS 1805347-26-5)
- 6-Bromo-4-(difluoromethyl)-5-hydroxynicotinic acid (CAS 1805349-76-1)
- 2-Bromo-3-(difluoromethyl)-5-hydroxyisonicotinic acid (CAS 1805410-92-7)
- N-(5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide (CAS 753468-25-6)
- 2-(Difluoromethyl)-4-fluoro-3-methylpyridine-5-carbonyl chloride (CAS 1806882-34-7)
- Phenyl(2-(triisopropylsilyl)oxazol-5-yl)methanone (CAS 648929-24-2)
- 2-(2-Ethoxyphenyl)-6-methylquinoline-4-carbonyl chloride (CAS 1160253-85-9)
- 1-(Propan-2-yl)cyclopropane-1-carbaldehyde (CAS 489468-09-9)
- 1-Isopropyl-3-methyl-1H-pyrazole-5-carboxylic acid (CAS 50920-68-8)
- 3-(2-Methoxyphenyl)piperidine (CAS 19737-63-4)
- 2-3-O-Isopropylidene-D-lyxonic acid-1-4-lactone (CAS 56543-10-3)
- 5-Chloro-3-(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 129177-21-5)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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